3-甲基腺嘌呤对细胞自噬的双重调节作用及nba1调控放射诱发细胞周期阻滞的初步研究

《3-甲基腺嘌呤对细胞自噬的双重调节作用及nba1调控放射诱发细胞周期阻滞的初步研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、分类号密级DUC编号硕士学位论文3-甲基腺嘌呤对细胞自噬的双重调节作用及NBA1调控放射诱发细胞周期阻滞的初步研究研究生姓名：杨艳丽指导教师姓名、职称：周平坤研究员张士猛副研究员学科、专业名称：卫生毒理学研究方向：辐射与放射医学2014年5月万方数据万方数据南华大学学位论文原创性声明本人声明，所呈交的学位论文是本人在导师指导下进行的研究工作及取得的研究成果。尽我所知，除了论文中特别加以标注和致谢的地方外，论文中不包含其他人已经发表或撰写过的研究成果，也不包含为获得南华大学或其他单位的学位或证书而使用过的材料。与我共同工作的同志对本研究所作的贡献均已在论文中作了明

2、确的说明。本人完全意识到本声明的法律结果由本人承担。作者签名：年月日南华大学学位论文版权使用授权书本学位论文是本人在南华大学攻读（博/硕）士学位期间在导师指导下完成的学位论文。本论文的研究成果归南华大学所有，本论文的研究内容不得以其它单位的名义发表。本人同意南华大学有关保留、使用学位论文的规定，即：学校有权保留学位论文，允许学位论文被查阅和借阅；学校可以公布学位论文的全部或部分内容，可以采用复印、缩印或其它手段保留学位论文；学校可根据国家或湖南省有关部门规定送交学位论文。同意学校将论文加入《中国优秀博硕士学位论文全文数据库》，并按《中国优秀博硕士学位论文全文数据

3、库出版章程》规定享受相关权益。同意授权中国科学信息技术研究所将本学位论文收录到《中国学位论文全文数据库》，并通过网络向社会公众提供信息服务。对于涉密的学位论文，解密后适用该授权。作者签名：导师签名：年月日年月日万方数据万方数据目录主要英文缩略语索引···························································I中文摘要········································································III英文摘要·················

4、························································V前言················································································1第一部分3-甲基腺嘌呤诱发HELA细胞自噬及抑制辐照细胞自噬的双重作用··········································································41材料与方法····························

5、·····································52结果·······································································93讨论·····································································154参考文献··································································17第二部分TALEN技术构建NBA1敲除质粒对··

6、······················201材料和方法·······························································212结果········································································313讨论········································································354参考文献······························

7、····································36第三部分NBA1调控放射诱发细胞周期阻滞的初步研究··········381材料和方法·······························································392结果········································································453讨论··························································

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