散结止痛巴布剂的质量标准、稳定性和药效学分析

散结止痛巴布剂的质量标准、稳定性和药效学分析

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时间:2018-11-29

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1、-Thequalitystandards.stabilityandpharmacodynamicsofsanjiezhitongcataplasmSpecialty:PharmacyAuthor:MaLinglingTutor:ProfessorLiWeiAbstractSanjieZhiTongCataplasmmainlybythere-building,diffusa,Prunella,ChuanWu,Araceae,borneolandothertraditionalChinesemedicinepreparedfromextractedw

2、ithEndometriosis,painswellingeffect.Forthepathogenesisofbreasthyperplasia,prescriptionweightfloor,diffusaQingrejiedu,swellingpainstasis,liverandstomachandintothesecondafter,thedirectbreastdisease;Prunellacanpassthemeans,theSanjiepain;icefilmXinsangochanneling,swellingandreliev

3、epain.Combinationofvariousdrugs,topicaldiseaselocation,makethedrugsdirectlytopatients,withdetoxificationSanjie,activestasis,Tongluozhitongachievements.Thisarticlefirstdescribedcataplasm’straits,andtherebuildingofherbsandmedicinalherbsPrunellavulgariswereTLC,borneolwereontheide

4、ntificationofgaschromatography.ChinesePharmacopoeiafortheitemsonthecheck,mainlydoneonalimitedinspectionofaconitine,containingpastevolumeinspection,excipientandadherencechecks.Finally,re-buildinginpolyphyllinsIandIIwerepolyphyllinscontentinspection,borneolborneolcontentinchecka

5、sitsqualityindicators.Theresultsshowedthat:SanjiepainCataplasmaheavyfloor,Prunellaandborneolactiveingredientscanbeextracted;checkitemswhichmeetthepharmacopoeiarequirements;polyphyllinscontentofeachpiecenotlessthan0.070mg,borneolcontentofeachnotlessthan10mg.OnthestabilityofCata

6、plasmSanjiepainpainforSanjiequalitystandardsCataplasmprojectwascarriedoutinthestabilitytestfactors(temperature,humidityandlightonitseffects),acceleratedstabilitytestandlong-termstabilitytest.Theresults---showedthat:Sanjiecataplasmpainresponsetolightandrelativelylargechangesin

7、temperature,theuseofaluminumfoilpackagingcanbasicallystable.Pharmacodynamicsforcataplasmwasstudied,usingintramuscularinjectionof exogenousestradiolbenzoateandprogesteronewayratmodelofmammaryglands, nippleswereobservedmorphologicalchangesinrats,usingRIADeterminationof experimen

8、talratmodelofeachgroupplasmaestradiol(E2),progesterone(P)cont

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