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1、高血压患者血清胱抑素C与冠心病的关系论文【摘要】目的探讨高血压患者血清胱抑素C(CysC)与冠心病的相关性。方法行冠脉造影检查的115例高血压患者,根据结果分为高血压冠心病组(66例)和高血压冠状动脉粥样硬化组(49例),检测血清脂蛋白a、载脂蛋白A、载脂蛋白B、高密度脂蛋白、低密度脂蛋白、三酰甘油、胆固醇、血肌酐、CysC等。分析冠心病与CysC的相关性,并用二元Logistic回归方法分析CysC、糖尿病、性别、年龄、身高、体重及IBM等因素与冠心病之间的相关性。结果高血压合并冠心病组CysC含
2、量明显高于冠状动脉粥样硬化组(P0.001),应用二元Logistic回归方法进行分析,发现CysC、脂蛋白a、载脂蛋白A、载脂蛋白B、高密度脂蛋白、低密度脂蛋白、三酰甘油、胆固醇、糖尿病、性别、年龄、体重指数与冠心病相关。结论CysC是高血压患者发生冠心病的独立危险因素,与血管的病变程度有正相关性,检测CysC是预测冠心病发病的有意义的指标。【关键词】血清胱抑素C;冠心病;高血压AbstractObjectiveTostudycorrelationofserumcystainC(CysC)andc
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