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1、社区H型高血压患者血清胱抑素C的检测结果分析张静夏锋奚齐红陶海琦孙丽艳(上海市闸北区彭浦镇社区卫生服务中心上海200072)【摘要】目的:探讨社区H型高血压患者血清胱抑素C的特点,以便及早控制高血压肾病的进展。方法:统计1404名H型高血压患者和1404名非H型高血压患者血清胱抑素C的检测结果,分析血清胱抑素C与性别、年龄、高血压级别等因素的相关性。结果:H型高血压组血清胱抑素C升高率(9.12%)高于非H型高血压组(6.12%),两组比较差异有统计学意义(P<0.05);性别亚组分析男女H型高血压且血清胱抑素C升高者比例为4.49%和4.63%,两组比较差异无统计学意义(P>0.05)
2、;年龄亚组分析H型高血压组,45〜54岁组、55〜64岁组、65〜74岁组和75岁以上组血清胱抑素C升高率分别为1.21%、1.57%、3.13%和3.21%,差异有统计学意义(P<0.05);高血压级别亚组分析1级、2级、3级H型高血压血清胱抑素C升高率分别2.92%、3.06%和3.13%,各组比较差异无统计学意义(P〉0.05)。结论:H型高血压较非H型高血压更易导致肾功能损伤。H型高血压患者中65岁以上人群肾功能损伤风险显著增加,性别和高血压级别不是H型高血压肾功能损害的危险因素。【关键词】H型高血压;健康体检;胱抑素C【中图分类号】R544.1【文献标识码】A【文章编号】209
3、5-1752(2016)11-0389-02AnalysisofserumcystatinCDetectionresultincommunitypatientswithH-typehypertensionZhangJing,XiaFeng,XiQihongjaoHaiqi,SunLiyanPengpu-towncommunityhealthservicecenterofZhabeiDistrict,Shanghai200072,China【Abstract】ObjectiveToinvestigatethecharacteristicsofserumcystatinCincommunit
4、ypatientswithH-typehypertension,inordertocontrolthedurationoftheearlyhypertensivenephropathy.MethodsThroughanalysisandcomparisonofserumcystatinCdetectionresultsbetween1404patientswithH-typehypertensionand1404patientswithoutH-typehypertension,analysecorrelationofserumcystatinCandgender、age、levelof
5、bloodpressureandotherfactors.ResultsH-typehypertensiongroup,serumcystatinCincreasedrate(9.12%)washigherthanthatofnonH-typehypertensiongroup(6.12%),thedifferencebetweenthetwogroupshasstatisticalsignificance(P<0.05);GendersubgroupanalysisofmaleandfemaleH-typehypertensionandserumcystatinCincrease
6、dratiowas4.49%and4.63%,thetwogroupshadnostatisticallysignificantdifference(P>0.05);AgesubgroupanalysisofH-typehypertensiongroup,45~54yearsoldgroup,55~64yearsoldgroup,65〜74yearoldandabove75yearsoldgroupelevatedserumcystatinCratewas1.21%,1.57%,3.13%and3.21%,thedifferencewasstatisticallysignifica
7、nt(P<0.05);thebloodpressurelevelofsubgroupanalysis1,2grade3,gradeH-typehypertensionofcystatinCincreaseratewas2.92%,3.06%and3.13%,therewasnosignificantdifference.(P>0.05).ConclusionH-typehypertensionismorelikelyto