microrna在慢性髓系白血病甲磺酸伊马替尼耐药中的作用及机制

《microrna在慢性髓系白血病甲磺酸伊马替尼耐药中的作用及机制》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、授予单位代码10089学号或申请号20151034中国图书分类号R557博士学位论文学术学位MicroRNA在慢性髓系白血病甲磺酸伊马替尼耐药中的作用及机制研究生：聂子元导师：罗建民教授专业：内科学二级学院：河北医科大学第二医院2018年4月目录中文摘要····························································································································1英文摘要····

2、························································································································7英文缩写··························································································································15研究论文MicroRN

3、A在慢性髓细胞白血病甲磺酸伊马替尼耐药中的作用及机制引言··························································································································16第一部分miR-202-5p在不同CML细胞株及CML患者中的表达差异前言·······································································

4、···················································17材料与方法············································································································18结果··························································································

5、································33附图··························································································································36附表··································································································

6、························46讨论··························································································································48小结··········································································································

7、················49参考文献·················································································································50第二部分miR-202-5p调控CML细胞对甲磺酸伊马替尼的敏感性前言························································································

8、··································52材料与方法············································································································52结果···························