急性脑梗死合并肾病综合征患者的临床特点及影像学分析

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1、授予单位代码10089学号或申请号20153235中国图书分类号R743.3HebeiMedicalUniversity硕士学位论文专业学位急性脑梗死合并肾病综合征患者的临床特点及影像学分析研究生：李雪纯导师：许蕾教授专业：神经病学二级学院：河北医科大学第二医院2018年3月目录中文摘要·········································································································10英文摘要······················

2、···················································································20研究论文急性脑梗死合并肾病综合征的临床及影像学特点前言·········································································································40材料与方法·····················································

3、·········································40结果·········································································································60附表·········································································································90讨论··············

4、···························································································11结论·········································································································14参考文献·······································································

5、···························14综述肾病综合征相关神经系统疾病的研究进展·····································17致谢·········································································································25个人简历············································································

6、·····························26中文摘要急性脑梗死合并肾病综合征患者的临床特点及影像学分析摘要目的：探索急性脑梗死合并肾病综合征的临床及影像学特点，分析可能的发病机制。方法：收集急性脑梗死合并肾病综合征患者51例，按照与病例组的基线资料相同的构成比选取同期住院的未合并肾病综合征的急性脑梗死病人49例作为对照组。收集所有患者的临床及影像学资料。结果：1.两组一般基线资料比较无统计学差异(P>0.05)。2.两组患者的血清胆固醇、甘油三酯、低密度脂蛋白、纤维蛋白原、抗凝血酶Ⅲ水平比较有统计学差异(P<0.05)。3.两组间

7、血管狭窄程度的比较，差异有统计学意义，病例组颅内血管狭窄程度高于对照组(P<0.05)。4.两组患者入院时神经功能缺损程度比较，差异无统计学意义(P>0.05)。5.病例组血管狭窄程度与血清白蛋白、24小时尿蛋白、血脂水平、肾病综合征病程的相关性分析：统计显示均无相关性(P>0.05)。6.病例组中仅13例(25.5%)采用了低分子肝素抗凝治疗。结论：1.合并肾病综合征的急性脑梗死患者存在严重的脂代谢异常及高凝状态。2.合并肾病综合征的急性脑梗死患者颅脑MRA表现出较为严重的血管狭窄，MRI表现为多发病灶的特点。关键词：急性脑梗死,肾病综合征,脂代

8、谢异常,高凝状态,血管狭窄1英文摘要Theclinicalandimagingfeaturesofpatientsinac