水飞蓟素胶囊成分鉴定及其对辛伐他汀体内药动学影响

水飞蓟素胶囊成分鉴定及其对辛伐他汀体内药动学影响

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大小:4.16 MB

页数:64页

时间:2018-11-08

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1、授予单位代码10089学号或申请号20152039中国图书分类号R969.3HebeiMedicalUniversity硕士学位论文学术学位水飞蓟素胶囊成分鉴定及其对辛伐他汀体内药动学影响研究生:李颖导师:董占军主任药师专业:药理学二级学院:河北省人民医院2018年3月目录中文摘要···········································································································1英文摘要···············

2、····························································································3英文缩写···········································································································6研究论文水飞蓟素胶囊成分鉴定及其对辛伐他汀体内药动学影响引言·································

3、··········································································7第一部分UPLC-Q-TOF-MS法分析鉴定水飞蓟素胶囊中14种化学成分前言···········································································································8材料与方法··········································

4、·····················································8结果·········································································································10附图·······································································································

5、··16附表·········································································································22讨论·········································································································24小结············································

6、·····························································24参考文献·································································································25第二部分UPLC-MS/MS法研究水飞蓟素对辛伐他汀及活性代谢物的体内药动学影响前言····························································

7、·············································27材料与方法·····························································································28结果·········································································································32附图··········

8、·······························································································35附表·························

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