性别与2型糖尿病合并骨质疏松患者骨密度改变的相关性研究

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1、性别与2型糖尿病合并骨质疏松患者骨密度改变的相关性研宄付彩雯朱晓荣吴艳(通讯作者)(四川省遂宁市屮心医院内分泌科四川遂宁629000)【摘要】目的：探讨性别与2型糖鉍病(type2diabetes,T2DM)合并骨质疏松(osteoporosis,OP)患者骨密度(Bonemineraldensity,BMD)改变的相关关系。方法：在四川省遂宁市屮心医院门诊及住院的T2DM合并0P患者100例作为研宄对象，采用双能X线骨密度测量仪测量正位腰椎和左侧股骨颈的骨密度值，比较不同性别患者骨密度之间的差异。结果：本研宄共纳入符合条件的T2DM合并0P患者100例，其中男性

2、46例,女性54例;平均年龄55.78±8.74岁；平均BMI为25.81±4.27。两组T2DM患者在平均年龄、平均体重指数、基础疾病情况、饮酒史方面差异均无统计学意义(P>；0.05),具有可比性，而吸烟患者的比例男性明显多于女性患者。女性T2DM合并0P患者的腰椎、股骨颈骨密度测定值明显低于男性患者，且差异有统计学意义(P<0.05)。T2DM合并0P患者的腰椎BMD、股骨颈BMD均与性别呈负相关关系(P<0.001)。结论：女性患者可能会增加T2DM继发0P的发病风险，而定期保持营养均衡、多摄入含钙的食物是预防的

3、治疗骨质疏松有效手段之一。【关键词】2型糖尿病；骨质疏松症；并发症；性别因素【中图分类号】R587.1【文献标识码】A【文章编号】2095-1752(2015)32-0115-02Studyonthecorrelationofbonemineraldensityinpatientswithtype2diabetesmellituscomplicatedwithosteoporosisFuCaiwenZhuXiaorongWuYan(EndocrinologyDepartmentSuiningCentralHospitalSuining629000SichuanCh

4、ina)【Abstract】ObjectiveToInvestigatethegenderandtype2diabetes(T2DM)mergerosteoporosis(OP)BMDpatients(BMD)changesincorrelation.MethodsSelect100casestype2diabetesmergerosteoporosisinSuiningCentralHospitalastheresearchobject,UsingX-raybonedensitymeasurementofbonemineraldensitytomeasureth

5、elumbarspineandleftfemoralneckvaluedualenergy.ResultsThisstudyincluded100patientswithT2DMcombinedwithOP,including46malesand55.78females,withanaverageageof54±8.74yearsold,withanaverageof25.81±4.27.ThetwogroupsofpatientswithT2DMinaverageage,averagebodymassindex,basicdiseas

6、e,drinkinghistorydifferenceswerenotstatisticallysignificant(P>0.05),withcanbecompared,andsmokingweretheproportionofmalewassignificantlyhigherthanthatofthefemalepatients.TheBMDoflumbarspineandfemoralneckinfemalepatientswithT2DMcombinedwithOPwassignificantlylowerthanthatofmalepatient

7、s,andthedifferencewasstatisticallysignificant(P<0.05).BMDandBMDofthelumbarspineinpatientswithT2DMandOPwerenegativelycorrelatedwithgender(P<0.001).ConclusionWomenmayincreasetheriskoftype2diabetesmellitus(T2DM)secondaryOP,andonaregularbasistomaintainbalancednutrition,eatmorecalciu

8、mfood