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1、ThePromiseoftheHumanPapillomavirusVaccineDoesNotConferImmunityAgainstEthicalReflection【关键词】HPV,#8226;,Cervical,cancer,#8226;,Ethics,#8226;,Justice ABSTRACT Therecentannouncementofanexperimentalvaccineagainsthumanpapillomavirus(HPV)hasraisedgreathopesandexpectations.Promisingtrialresu
2、lts,hoatedissemination.Althoughlaymediamightvieoreplicatedethicalrealityexists,touchinguponpublicknoentofanexperimentalvaccineagainsthumanpapillomavirus(HPV)hasraisedgreathopesinthelaypressandarecentarticleinTheOncologist[15].GiventheepidemiologyandpathogenesisofHPVandHPV-associateddis
3、eases,suchexpectationsareunderstandable.HPVinfectionisoneofthemostmonsexuallytransmittedinfectionsately20millioninfectedmenandenintheU.S.[6].Althoughmostinfectionsaretransient,persistentonescanleadtoanogenitaliseofavaccinetoreducetheincidenceofHPVanditssequelae,hoentandimplementation.A
4、mongtheseconcernsarethecriticalneedforpubliceducationaboutHPVanditsconsequences,accesstohealthcareresources,healthpracticesthatmightreinforceproblematicstereotypes,andrequirementsforinformedconsent. HPVANDCERVICALCANCER Cervicalcancerisoneoftheleadingcancersamongen.erckCo.,Inc.(aking
5、surethatresourcesdevotedtotheintroductionofanHPVvaccinedonotdisplacesecondarypreventionprogramsisofutmostimportance. HPVandoreover,avaccineforasexuallytransmitteddiseasedirectedonlytoenmightreinforcetheenalreadybearadisproportionateburdenformattersofreproductivedecisionmaking[26,27].S
6、tudiesshoendonotperceivethemselvestobesusceptibletoHPVanddonotbelieveHPVinfectiontobeasevereproblemforthemselves[25].erckpresenteditsinterimphaseIIIresults,somequestionedberofsexualpartnersamongadolescents―in2003,46.7%ofhighschoolstudentshadhadsexualintercourse―theyhavebeenidentifiedas
7、agroupatrisk[33].Researchershavethussuggestedthatgirlsbetehavearguedthatparents’approvalofHPVimmunizationmightbehardtoobtainbecausechildrenedaboutitspurpose[2932].Somebelievethiscouldpromoteconversationsaboutsexualbehaviorthatparentsmightbeuneparentsberofparentslikelytodenyconsentfor
