新生儿不典型化脓性脑膜炎26例临床特点回顾性分析

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1、新生儿不典型化脓性脑膜炎26例临床特点顾性分析［摘要］目的探究26例新生儿不典型化脓性脑膜炎临床特点。方法整群选取回顾性分析该院2013年2月-2015年4月收治的26例罕见性新生儿不典型化脓性脑膜炎临床资料，分析患儿发病时临床表现、诊断方法、治疗方法及治疗效果等。结果新生儿不典型化脓性脑膜炎发病初期临床症状不明显，实验室检查一般难以作出正确的诊断，脑脊液检查结果和典型的化脓性脑膜炎有较大的差异，临床诊断该病难度较大；患儿经抗感染、降颅压、肾上腺素、抗惊厥等对症治疗以后，患儿均治愈出院，无死亡病例，治疗后出现神经系统后遗症3

2、例，其中合并硬膜下积液1例，癫痫1例。结论新生儿不典型化脓性脑膜炎临床症状不典型，容易出现误诊、漏诊，研究清楚新生儿不典型化脓性脑膜炎临床特点，可为临床诊断、治疗提供可靠依据，以提升治疗治疗效果，降低死亡率，改善患儿预后。［关键词］新生儿不典型化脓性脑膜炎；临床特点；回顾性分析；症状分类号］R54［文献标识码］A［文章编号］1674-0742(2016)01(a)-0118-03RetrospectiveAnalysisofClinicalCharacteristicsof26CaseswithAtypicalPurulen

3、tMeningitisinNewbornsZHANGNa-naPediatrics,Hechifirstpeople’sHospital,546300China[Abstract]ObjectiveTodiscusstheclinicalcharacteristicsof26caseswithAtypicalpurulentmeningitisinnewborns.MethodsTheclinicalmaterialsof26caseswithrareatypicalpurulentmeningitisinnewbornst

4、reatedinourhospitalfromFebruary2013toApril2015wereretrospectivelyanalyzedandtheclinicalperformance,diagnosticmethod,treatmentmethodandtreatmenteffectofthepatientswereanalyzed.ResultsTheclinicalsymptomsofatypicalpurulentmeningitisinnewbornsattheinitialstagewerenotob

5、vious,thecorrectdiagnosiswasdifficulttobemadebylaboratoryexamination,thedifferenceincerebrospinalfluidexaminationresultsbetweenatypicalpurulentmeningitisinnewbornsandtypicalpurulentmeningitis,thedifficultyintheclinicaldiagnosisofthediseasewasbig；afterthesymptomatic

6、treatmentsofanti—infection,loweringintracranialpressure,adrenalineandanticonvulsants,allpatientswerecuredanddischargedwithoutdeathcases，aftertreatment，3caseswerewithneurologicalsequelae,including1casewithsubduraleffusion,1casewithepilepsia.ConclusionTheclinicalsymp

7、tomsofatypicalpurulentmeningitisinnewbornswerenottypicalandpronetomisdiagnosisandmisseddiagnosis,andtheclearresearchoftheclinicalcharacteristicsofatypicalpurulentmeningitisinnewbornscanprovidereliablebasisforclinicaldiagnosisandtreatmentinordertoimprovethetreatment

8、effects,decreasethedeathrateandimprovetheprognosisofpatients.［Keywords］Atypicalpurulentmeningitisinnewborns；Clinicalcharacteristics；Retrospective