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1、基层医院幽门螺杆菌与脑卒中的关联(1.新建县人民医院消化内科江丙南昌330100);(2.新建县人民医院感控科江丙南昌330100);(3.新建县人民医院神经内科江西南昌330100)【摘要】目的:探讨幽门螺杆菌感染和脑卒中发生之间的关系,以及其可能存在的机制。方法:选择我院2012年3月至2014年5月收治的30例脑卒中患者为观察组,另选同期30例健康成人为对照组,清晨空腹取静脉血5ml,监测三酰甘油(TC)、总胆固醇(TG),低密度脂蛋白(LDL)、高密度脂蛋白(HDL),分析血脂和Hp感染之间的相关性。结果:观察组Hp-IgG阳性率为70.0%,对照
2、组Hp-IgG阳性率为26.7%,差异显著(PC0.05)。两组患者中,Hp-IgG阳性患者,TG、TC和LDL均显著高于Hp-IgG阴性患者,差异显著(P<0.05),而HDL则明显低于阴性患者(P<0.05),观察组的HP-IgG和LDL、TC呈正相关性,(P<0.05),和HDL呈负相关性(PC0.05)。结论:脑卒中和Hp感染呈密切相关性,机制可能是脂质代谢受到影响,经代谢途径起作用。【关键词】幽门螺杆菌;脑卒中;相关性【中图分类号】R743.33【文献标识码】B【文章编号】1003-5028(2015)7-0206-02Thecorrelatio
3、nbetweenHelicobacterPylori'sandCerebralApoplexyinPrimaryHospitalYushanGongl,ZhiqianLuol,MeixiaJiel,HuipingXiong2,GuangmingYu3(1.DepartmentofGastroenterology,thePeoplesHospitalofXinjianCounty,NanchangJiangxi330100;2.DepartmentofInfectionControl,thePeople’sHospitalofXinjianCou
4、nty,NanchangJiangxi330100;3.DepartmentofNeurology,thePeople’sHospitalofXinjianCounty,NanchangJiangxi330100)【Abstract】Objective:ToexploretherelationshipbetweenHelicobacterpylori’sandcerebralapoplexyaswellasthepotentialmechanismsbetweenthem.Methods:30hospitalizedpatients
5、withcerebralapoplexyinourhospital,fromMarch2012toMay2014,weretakenasexperimentgroup.Meanwhile,other30healthycaseswereservedascontrolgroup.5mlfastingvenousbloodsweredrawnfromallthesesubjectsinthemorning,supervisingtheirHp-IgG'triglycerides(TC),cholesterol(TG),lowdensitylipoprotein(
6、LDL)aswellashighdensitylipoprotein(HDL,soastoanalyzethecorrelationbetweenbloodlipidsandHpinfection.Results:ThepositiverateofHp-IgGintheexperimentgroupwas70.0%,while26.7%inthecontrolgroup,whichshowssignificantdifferences(P<0.05,respectively)•ThelevelsofTG,TCaswellasLDLinallsubjects
7、withpositiveHp-IgGwereallhigherthanthosewithnegativeHp-IgG,whilethelevelofHDLwaslowerwhencompared(P<0.05,respectively).Therefore,intheexperimentgroup,thereispositiverelationshipbetweenthepositiverateofHp-IgGandthelevelsofbothLDLandTC,whereasnegativerelationshipbetweenthepositivera
8、teofHp-IgGandthehighlevelofHDL(P<