健脾益坤方对围绝经期综合征大鼠影响的实验研究

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1、万方数据英文摘要Therewasnosignificantdifferencebetweenthecombinationtherapygroupandtheshamoperationgroupintheratsuterusweightcoefficient(P>0．05)．6Changesofuterusmorphologyandmetrology6．1ToobservethepathologicalmorphologyofuterusObservationunderthelightmicroscope：Endometrialepithelialcel

2、lsandglandularepithelialcellsoftheshamoperationgroupwerehighcolumn，glandulartissuedenser，glandularcavitysizes，muscularfibersarrangedregularlyconsistent，theserosallayerwassmooth．Themodelcontrolgroupendometriumobviouslyatrophiedandthinned，glandulartissuedecreased，glandularcellsmos

3、tlywerelowcolumnar，musclelayerbecomesthinner，muscularfiberarrangeddisorder，theserosawasnotsmooth．Comparedwiththemodelgroup，chinesemedicinetreatmentgroupendometriumthickenedmildly，glandulartissueincreased，muscularfiberarrangedregularly，whiletheserosabecamesmooth．Comparedwiththemo

4、delgroup，theendometrialhyperplasiaofwesternmedicinetreatmentgroupandthecombinationtherapygroupwasobvious，endometrialepithelialcellswashighcolumnar，glandulartissuedenser，musclefiberswerearrangedinrules，serosawassmooth．6．2TheresultsofendometrialmorphometryComparedwiththeshamoperat

5、iongroup，themodelcontrolgroupendometrialthicknessanduterinewallthicknessdecreasedsignificantly，thedifferencewasstatisticallysignificant(P<0．01)．Comparedwithmodelgroup，uterusmorphologymeasurementindexesofthetreatmentgroupthickenedobviously，thedifferencewasstatisticallysignificant

6、(P<0．o1)．Conelusions：1Menopausalhotflashes，endocrinedisorders，histopathologicalchangesdemonstratedthatperimenopausalsyndromeanimalmodelisestablishedsuccessfully．7万方数据英文摘要2JPYKdecoctioncanimprovethegeneralconditionofperimenopausalrats，shortenestrouscycle，promotethemtorecovernorma

7、lly．Changesofserumsexhormonelevels，theweightcoefflcientofuterus，uterustissuemorphologyandmetrologyofthetreatmentgroupratsshowthathastheadvantagesofchinesemedicineinimprovingendocrineandovarianfunction，whilethetreatmentmedicinecanlowertherectaltemperatureandthelevesofcalcitoninge

8、ne—relatedpeptidetoimprovehotflashesandothersym