galectin-3和cd105在胃癌进展过程中的表达

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1、授予单位代码10089学号或申请号16100中国图书分类号R735.2HebeiMedicalUniversity硕士学位论文学术学位Galectin-3和CD105在胃癌进展过程中的表达研究生：高玉涛导师：刘丽教授专业：内科学二级学院：河北医科大学第二医院2018年3月目录中文摘要··········································································································1英

2、文摘要··········································································································4英文缩写··········································································································8研究论文Galectin-3和CD105在胃癌进展过程中的

3、表达前言··········································································································9材料与方法······························································································10结果····································

4、······································································15附图··········································································································17附表··································································

5、········································21讨论··········································································································25结论································································································

6、··········27参考文献··································································································27综述CD105与肿瘤的研究进展····································································31致谢···············································

7、···································································43个人简历··········································································································44Galectin-3和CD105在胃癌进展过程中的表达摘要胃癌(gastriccancer，GC)源自于胃黏膜上皮细胞，是一种常见的消化道

8、恶性肿瘤，其恶性程度高，发病率、病死率较高，我国胃癌5年相对生存率在最近的调查中显示仅有27.4%，而早期胃癌术后的生存率却高达90%以上，故而早期发现、早期治疗显得十分重要。随着分子生物学和基因技术的发展、提高，众多学者开始从基因水平来研究胃癌，试图寻找胃癌可靠的诊断标志物及新的治疗靶点。半乳糖血凝素-3蛋白(Galectin-3)属于半乳糖凝集素家族的成员，参与了包括调节细胞的生长分化、细胞的黏附凋亡和血管形成等诸多人体多种生理及和病理过程，还被发现参与肿瘤细胞的侵袭和转移。Galectin