晚期卵巢癌肿瘤细胞减灭术后静脉化疗联合腹腔热灌注治疗的临床疗效分析

《晚期卵巢癌肿瘤细胞减灭术后静脉化疗联合腹腔热灌注治疗的临床疗效分析》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、授予单位代码10089学号或申请号20153074中国图书分类号R711.75HebeiMedicalUniversity硕士学位论文专业学位晚期卵巢癌肿瘤细胞减灭术后静脉化疗联合腹腔热灌注治疗的临床疗效分析研究生：胡晓娜导师：赵素芬教授专业：妇产科学二级学院：河北医科大学第二医院2018年3月目录中文摘要···············································································1英文摘要···································

2、············································2英文缩写···············································································4研究论文晚期卵巢癌肿瘤细胞减灭术后静脉化疗联合腹腔热灌注治疗的临床疗效分析前言···············································································5资料与方法····················

3、··················································7结果···············································································9附图···············································································11附表·······················································

4、························13讨论···············································································15结论···············································································17参考文献·········································································17综述

5、晚期卵巢癌治疗进展·······················································21致谢·····················································································31个人简历···············································································32中文摘要晚期卵巢癌肿瘤细胞减灭术后静脉化疗联合腹腔热灌注治疗的临床

6、疗效分析摘要目的：探讨晚期卵巢癌肿瘤细胞减灭术后静脉化疗联合腹腔热灌注治疗的临床疗效和不良反应，为临床治疗提供参考依据。方法：回顾分析2015年1月至2017年10月在河北医科大学第二医院就诊的晚期卵巢癌患者29例，其中观察组14例（肿瘤细胞减灭术+多西他赛、奥沙利铂静脉化疗+腹腔热灌注化疗），对照组15例（肿瘤细胞减灭术+多西他赛、奥沙利铂静脉化疗+腹腔热灌注），比较两组患者的临床疗效、腹水控制情况、不良反应、复发及生存等情况。结果：观察组与对照组在肿瘤控制、PFS、OS、3疗程化疗内CA125水平上差异均无统计学意义(P>0.05)；两

7、组腹水控制比较，观察组优于对照组，差异有统计学差异（P<0.05）；毒副反应中观察组消化道症状稍高，差异有统计学差异（P<0.05）；其他不良反应无明显差异(P>0.05)。结论：腹腔热灌注化疗相比于腹腔热灌注可减轻晚期卵巢癌腹水情况，提高患者的生活质量，值得临床推广应用关键词：晚期卵巢癌，腹腔热灌注化疗，腹腔热灌注，静脉化疗，联合化疗1英文摘要ClinicalefficacyofpostoperativeintravenouschemotherapycombinedwithHyperthermicintraperitonealtherap

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