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1、冠心病介入治疗进展-2008高润霖CardiovascularInstitute＆FuWaiHospitalCAMS,PUMCSafetyofDESRevascularization:CABGorPCITreatmentforbifurcation:sampleisbetter?Fractionalflow-reserveforguidingNewgenerationofDESKirtaneAJ,StoneGW.Comprehensivemeta-analysisofDESvsBMSrandomizedtrialsandreg
2、istries;March28,2008;Chicago,IL.MEGAmeta-analysisStudytypePatients,nTrials,nRelativeriskpRCT:all8867210.970.72aRCT:on-label4818101.050.69aRCT:off-label4049120.840.24aRegistries161 232280.80<0.001ba.Fixed-effectsmodelb.Random-effectsmodelAll-causemortalityKirtaneAJ,S
3、toneGW.Comprehensivemeta-analysisofDESvsBMSrandomizedtrialsandregistries;March28,2008;Chicago,IL.MIStudytypePatients,nTrials,nRelativeriskpRCT:all8850200.940.54aRCT:on-label431891.030.82aRCT:off-label4532120.770.19bRegistries129 955240.890.023ba.Fixed-effectsmodelb.
4、Random-effectsmodelMEGAmeta-analysisKirtaneAJ,StoneGW.Comprehensivemeta-analysisofDESvsBMSrandomizedtrialsandregistries;March28,2008;Chicago,IL.Target-vesselrevascularizationStudytypePatients,nTrials,nRelativeriskP*RCT:all7291160.45<0.001RCT:on-label461890.53<0.001R
5、CT:off-label267380.38<0.001Registries73 819170.53<0.001*Random-effectsmodelMEGAmeta-analysisSafetyofDESRevascularization:CABGorPCITreatmentforbifurcation:sampleisbetter?Fractionalflow-reserveforguidingPCIinmulti-vesseldiseaseNewgenerationofDESThesafetyandeffectivene
6、ssofthe*TAXUS®Express2®StentSystemhavenotbeenestablishedinthefollowingpatientpopulations:patientswithvesselthrombusatthelesionsite;patientswithcoronaryarterylesionslongerthan28mmorrequiringmorethanoneTAXUSStent;lesionslocatedintheunprotectedleftmaincoronaryartery,or
7、lesionslocatedatabifurcation/trifurcation;patientswithmoderateorseverecalcificationinthelesionorachronictotalocclusion;orpatientswithmulti-vesseldisease.TheTAXUSExpressStentSystemhasnotbeenspecificallyindicatedforpatientswithdiabetes.SYNTAX(SYNergybetweenPCIwithTAXU
8、S*andcardiacsurgery)PatientProfilingLocalHeartteam(surgeon&interventionalcardiologist)assessedeachpatientinregardsto:Patient’soperativeris
