百白破疫苗接种不良反应原因分析及预防对策

《百白破疫苗接种不良反应原因分析及预防对策》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、百白破疫苗接种不良反应原因分析及预防对策谢亚利李汉华李贺兰肖瑞[摘要]目的：分析百白破疫苗预防接种不良反应的原因和预防对策。方法：对接种吸附百白破疫苗出现不良反应的病例进行回顾性分析总结。结果：18~24月龄加强免疫组儿童不良反应发生率（含局部反应发生率、全身反应发生率）高于3~6月龄基础免疫组儿童（P＜0.01），夏秋季不良反应发生率高于冬春季（P＜0.01），吸附全细胞百白破联合疫苗不良反应发生率高于吸附无细胞百白破联合疫苗（P＜0.01）。结论：接种吸附百白破疫苗时要注意充分摇匀药液，选择正确的接种部位和接种途径，严格消毒接种部位，并做好接种前后的卫生保健宣教工作；遇

2、高温天气适当推迟接种；推荐使用吸附无细胞百白破联合疫苗。[关键词]预防接种；不良反应；吸附全细胞百白破联合疫苗；吸附无细胞百白破联合疫苗。Diphtheria-Pertusis-Tetanusvaccinecausesadversereactionsandpreventivemeasures.XIEYa-li,LIHan-hua,LIHuo-lan,etal.(DongkenghospitalofDongguancity,Dongguan523451,Guangdong,China)Abstract：ObjectiveAnalysisofDiphtheria-Pertusi

3、s-Tetanusvaccine-preventablecauseofadversereactionstovaccinationandpreventivemeasures.MethodsAdsorptionofDiphtheria-Pertusis-Tetanusvaccinationvaccineadversereactioncaseswereretrospectivelyanalyzedandsummarized.Result18~24-month-oldchildrentostrengthentheimmunegrouptheincidenceofadverserea

4、ctions(includingtheincidenceoflocalreactions,theincidenceofsystemicreaction)washigherthan3to6-month-oldchildrenbasedonimmunohistochemistry(P＜0.01),summerandautumnishigherthantheincidenceofadversereactionswinterandspring(P＜0.01),Adsorptionofwhole-cellDiphtheria-Pertusis-Tetanusvaccinetheinc

5、idenceofadversereactionshigherthantheadsorptionofacellularDiphtheria-Pertusis-Tetanusvaccine(P＜0.01).ConclusionDiphtheria-Pertusis-Tetanuvaccineadsorbedvaccineshakentotheattentionofthefullsolution,choosethecorrectwayofimmunizationandvaccinationsite,strictdisinfectionofinjectionsite,anddoag

6、oodjobbeforeandaftervaccinationofhealthcareandeducation;caseofhightemperaturesappropriatetodefervaccination;recommendtheuseofadsorptionacellularDiphtheria-Pertusis-Tetanuvaccine.KeyWordsVaccination;Adversereactions;Adsorbedwhole-cellDiphtheria-Pertusis-Tetanusvaccine;AdsorptionacellularDip

7、htheria-Pertusis-Tetanusvaccine.吸附百白破联合疫苗是由全细胞或无细胞百日咳菌苗原液、精制白喉类毒素及精制破伤风类毒素用氢氧化铝吸附制成的混合疫苗，用于预防百日咳、白喉和______________________________________________________作者单位：东莞市东坑医院，广东，东莞，523451作者简介：谢亚利（1971-），男，本科，公卫主管医师，疾病预防控制locatedintheTomb,DongShenJiabang,deferthenextda