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时间:2018-08-04
《基于纳米技术表面改性气道自扩张金属支架治疗气道狭窄临床研究》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、基于纳米技术表面改性气道自扩张金属支架治疗气道狭窄临床研究关键字:基于纳米技术表面改性气道自扩张金属支架治疗气道狭窄临床研究本文为Word文档,感谢你的关注! [摘要]目的探�基于纳米技术表面改性气道自扩张金属支架治疗气道狭窄临床疗效。方法收集我院呼吸内科或其他科室收治的气道狭窄患者42例,随机分为试验组和对照组,各21例。两组患者均予以金属支架置入术,对照组予以镍钛记忆合金支架治疗;试验组予以基于纳米技术表面改性气道自扩张金属支架治疗。治疗结束后,比较两组患者临床疗效、气道狭窄段腔径、气促指数、肺功能检测、再狭窄发生率、呼吸困难指数分级以及并发症发生情况。结果治疗后两组患者气道狭窄
2、段腔径、FVC以及FEV1水平升高,气促指数降低(P<0.05);与对照组相比,试验组临床总有效率较高,试验组气道狭窄段腔径、FVC以及FEV1水平较高,气促指数较低,试验组0~Ⅰ级呼吸困难例数较多,Ⅱ~Ⅴ级呼吸困难例数较少,差异有统计学意义(P<0.05),试验组患者的并发症发生率明显低于对照组,差异有统计学意义(P<0.05)。结论基于纳米技术表面改性气道自扩张金属支架治疗气道狭窄临床疗效显著,可解除气道狭窄,改善呼吸困难。 [关键词]纳米技术表面改性;气道自扩张;金属支架;气道狭窄 []R562[]A[]1673-9701(2017)11-0014-05 Clinicals
3、tudyonthetreatmentoftrachealstenosiswithairwayself-expandingmetalstentbasedonnano-technologysurfacemodification WUFengjie1YAOYangwei1CHENEnguo2 1.DepartmentofRespiratoryMedicine,JiaxingSecondHospitalinZhejiangProvince,Jiaxing314000,China;2.DepartmentofRespiratoryMedicine,SirRunRunShawHospitalA
4、ffiliatedtoSchoolofMedicine,ZhejiangUniversity,Hangzhou310006,China [Abstract]ObjectiveToexploretheclinicalefficacyofairwayself-expandingmetalstentinthetreatmentoftrachealstenosisbasedonnano-technologysurfacemodification.MethodsAtotalof42patientswithairwaystenosiswhowereadmittedtothedepartmento
5、frespiratorymedicineorotherdepartmentswerecollectedandrandomlydividedintotheexperimentalgroupandthecontrolgroup,with21patientsineachgroup.Bothgroupsweregivenmetalstentimplantation.ThecontrolgroupwasgivenNi-Timemoryalloystent,andtheexperimentalgroupwasgivenairwayself-expandingmetalstentbasedonnan
6、o-technologysurfacemodification.Afterthetreatment,theclinicalefficacy,thelumendiameteroftheairwaystenosis,theshortnessofbreathindex,thetestoflungfunction,theincidenceofre-stenosis,theclassificationofdyspneaindexandtheoccurrenceofcomplicationswerecomparedbetweenthetwogroups.ResultsAfterthetreatme
7、nt,thelumendiameteroftheairwaystenosis,thelevelsofFVCandFEV1wereincreasedandtheshortnessofbreathindexwasdecreasedinbothgroups(P<0.05);comparedwiththecontrolgroup,thetotaleffectiverateintheexperimentalgroupwashigher.Thelumend
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