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1、呼吸ICU危重感染患者血清肌钙蛋白I浓度与APACHEⅢ评分及预后关系的研究何远强郑玉龙周黎阳万玉峰刘淑丁宗励(1.江苏淮安市第二人民医院呼吸内科淮安223002）[摘要]【目的】探讨呼吸ICU(RICU)危重感染患者血清肌钙蛋白(cTnI)浓度改变与急性生理学及慢性健康状况评分Ⅲ(APACHEⅢ)及预后的关系。【方法】检测120例入住RICU的危重感染患者的血清cTnI浓度,并对危重感染患者进行APACHEⅢ评分;分析血清cTnI浓度与APACHEⅢ评分及死亡率的关系。【结果】120例患者血清cTnI平均浓度为(0.25±0.12)ng/mL,存活组血清cTnI浓度(0
2、.14±0.09)ng/mL,死亡组血清cTnI浓度(1.72±0.53)ng/mL,两组比较差异有显著性(P<0.01);120例患者平均APACHEⅢ评分(48.6±18.7)分,存活组APACHEⅢ评分(37.6±22.2)分,死亡组APACHEⅢ评分(65.2±29.4)分,两组比较差异有显著性(P<0.01)。血清cTnI浓度与APACHEⅢ评分呈正相关(r=0.7012,P<0.01),随各组血清cTnI浓度增高,APACHEⅢ评分值亦增高(F=28.69,P<0.01),各组死亡率也随2之增高(χ=22.18,P<0.01)。【结论】呼吸ICU危重感染患者血
3、清cTnI浓度和APACHEⅢ评分明显增高,对判断病情及预后有一定的作用。[关键词]急性生理学及慢性健康状况评分Ⅲ;肌钙蛋白;危重病;预后StudyontherelationshipbetweenserumtroponinandAPACHEⅢscores,theprognosisofthepatientsinrespiratoryintensivecareunit，HeYuanqiang(DepartmentofRespiratoryMedicine,theHuaianHospitalAffiliatedtoxuzhouMedicalcollege,Jiangsu,223
4、002China)[Abstract]【Objective】ToexploretherelationshipbetweenacutephysiologyandchronichealthevaluationⅢ(APACHEⅢ)scoresandserumtroponinconcentration,prognosisofpatientsadmittedtorespiratoryintensivecareunit。【Methods】TheAPACHEⅢscoresofthepatientswereassessed.Theserumtroponinlevelsweremeasur
5、edin120cases,andtherelationshipbetweenAPACHEⅢscoresandserumtroponinconcentration,Mortalitywereanalyzed.【Results】TheaverageAPACHEⅢscoreofthe120caseswas(48.6±18.7).TheAPACHEⅢscore(37.6±22.2)inthesurvivalgroupwassignificantlylowerthanthat(65.2±29.4)inthedeadgroup,P<0.01.Theaverageserumtropon
6、inconcentrationofthe120caseswas(0.25±0.12)ng/mL.Thetroponinconcentrationinthesurvivalgroupwas(0.14±0.09)ng/mL,whichwassignificantlylowerthan(1.72±0.53)ng/mLinthedeadgroup,P<0.01.ThehighertheAPACHEⅢscoreswas,thehighertheserumtroponinconcentration2was(F=28.69,P<0.01)andthemortality(χ=22.18,
7、P<0.01)【.Conclusion】SerumtroponinlevelsandAPACHEⅢofthepatientsinRICUwereobviouslyhigherthanthoseofthesurvivalhealthypeople,whichplaysanimportantroleinjudgingtheconditionsandprognosisofpatientsadmittedtoRICU[Keywords]AcutephysiologyandchronichealthevaluationⅢ(APACHEⅢ
