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ID:11178939
大小:33.50 KB
页数:9页
时间:2018-07-10
《慢性阻塞性肺疾病合并支气管肺癌临床探究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、慢性阻塞性肺疾病合并支气管肺癌临床探究【摘要】目的探讨慢性阻塞性肺病(COPD)合并原发性支气管肺癌的发病机制、临床特征、早期诊断及治疗方法。方法对48例COPD合并肺癌患者发病年龄、性别、临床表现及选择的治疗方法进行回顾性分析。结果48例患者中,男39例(81.3%),女9例(18.7%),大量吸烟史37例(77.1%)。病理类型:鳞癌26例(54.2%),腺癌11例(22.9%),小细胞癌5例(10.4%),未定型癌6例(12.5%)。TNM分期:I期2例(4.2%),Ⅱ期3例(6.2%),ⅢA+B期32例(66.7%),Ⅳ期11例(22.9%)。出现可疑症状到确诊时间:1个月
2、内1例(2.1%),2~6个月29例(60.4%),7~12个月12例(25.0%),1年以上6例(12.5%)。治疗方法:手术切除2例(4.2%),姑息性放和/或化疗13例(27.1%),射频消融治疗5例(10.4%),中医治疗15例(31.3%),仅做对症、支持治疗9例(18.7%),放弃治疗4例(8.3%)。结论9COPD患者合并肺癌的症状无特异性,早期确诊率低。COPD患者伴胸痛、血痰、咳嗽性质的改变、胸腔积液、进行性消瘦应警惕合并肺癌的可能;定期X线和痰脱落细胞筛查对COPD合并肺癌的早期发现有一定的临床意义;胸部CT和纤支镜检查对COPD合并肺癌的临床诊断价值大。COP
3、D合并肺癌的治疗以改善生活质量为主。【关键词】慢性阻塞性肺病;原发性支气管肺癌Ananalysisof48casesofchronicobstructivepulmonarydiseasemergerdlungcancerZHANGShuang-sheng,ZHONGChun-yi,CHENXiao-ying.TheAffiliatedJiangmenHospitaltosunyat-senuniversityJiangmencenterHospital,GuangdongJiangmen529030,China【Abstract】ObjectiveToexplorepossibl
4、epathogenesis,clinicalfeatureandearlyperioddiagnosisofchronicobstructivepulmonarydisease(COPD)mergeredprimarybronchogeniccarcinoma.MethodsAtotalof48patientswithCOPDmergeredlungcancerwereanalysed,includingpossiblepathogenesis,clinicalfeatureandearlyperioddiagnosis.ResultsInallof48patients,39wer
5、emales(81.3%)and9werefemales(18.7%),37caseswithsmokinghistory(77.1%).Pathologicexaminationshowed26casesofsquamouscellcarcinoma(54.2%),11casesofaciniccellcarcinoma(22.9%),5casesofsmallcellcarcinoma(10.4%),and6caseswerenotbeconfirmed(12.5%).AccordingtoTNMclassificationof9pulmonarycarcinoma,there
6、were2casesinstageI(4.2%),3casesinstageII(6.2%),32casesinstageIIIA+B(66.7%)and11casesinstageIV(22.9%).Thenumbersofallof48casesgivenexcision,radiotherapyand/orchemotherapy,chinesemedicine,radiofrequencytherapy,Supportivetreatmentandgivingupanytherapywere13(27.1%),15(31.3%),5(10.4%),9(18.7%),4(8.
7、3%)respectively.ConclusionsTherewerenospecificsymptomsinthepatientswithchronicobstructivepulmonarydisease(COPD)mergeredprimarybronchogeniccarcinoma,soearlyperioddiagnosisratewasverylow..PatientswithCOPDcompaniedchestpain,sputumblood,the
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