欢迎来到天天文库
浏览记录
ID:10083349
大小:34.50 KB
页数:0页
时间:2018-05-24
《心脏术后继发嗜麦芽窄食单胞菌肺部感染临床及药敏分析》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、【摘要】目的:分析和总结体外循环心脏手术后嗜麦芽窄食单胞菌(SMA)肺部感染的临床特点及药敏情况。方法:对36例体外循环心脏手术后继发SMA肺部感染的临床资料进行统计分析,分析所收集的术后经气管插管吸出物培养分离出的36株SMA的药敏材料。结果:36例患者均存在呼吸机应用时间超过3d、应用了广谱抗生素;伴有多器官功能不全综合症(MODS,833%)、混合感染(611%)、体外循环时间超过2h(583%)也是本病高危因素;该菌对常用抗生素广泛耐药,敏感率大于50%的抗生素依次为米诺环素(852%),替卡西林+克拉维酸(815
2、%),复方磺胺甲唑(742%),加替沙星(688%),头孢哌酮+舒巴坦(649%),环丙沙星(635%),哌拉西林+三唑巴坦(630%),左氧氟沙星(569%)。结论:嗜麦芽窄食单胞菌已成为体外循环心脏手术后呼吸机相关性肺炎的重要致病原菌之一,多发生在心功能差、体外循环时间长、术后呼吸机使用时间长、合并MODS、混合感染及术后应用碳青霉烯类抗生素的病人。感染后,可选用抗菌药物的范围较窄,治疗相对困难。【关键词】心脏外科手术嗜麦芽窄食单胞菌微生物敏感性试验Analysisofclinicalcharacteristicsa
3、nddrugsensitivitytestsofpulmonaryinfectioncausedbystenotrophomonasmaltophiliafollowingcardiosurgery/XUWei
4、jiang,LIUBin//ChineseJournalofCardiovascularRehabilitationMedicine,2007,16(3):277Abstract:Objective:Toanalyzetheclinicalcharacteristicsofpulmonaryinfectioncausedby
5、stenotrophomonasmaltophilia(SMA)followingcardiosurgeryandtoinvestigatetheantibioticsensitivityofSMAstrains.Methods:Retrospectivestudyoftheclinicaldataof36caseswithpulmonaryinfectioncausedbySMAfollowingcardiosurgerywasperfprmed.ThedataofdrugsensitivityagainstSMAstrainsb
6、ycultureofsputumfromthetipsoftrachealtubwereanalyzed.Results:Allof36casesusethemechanicalventilationwasmorethan3daysandusedwithextend
7、spectrumantibiotics.TheMODS(833%),mixedinfection(611%)andtimeofcardiopulmonarybypass(CPB)more2h(583%)werealsotheriskfactors.Thedrugs
8、ensitivitytestinvitroshowedthatthesestrainsweremultiresistanttocommonlyusedantibiotics,anddrugswhosesensitiveratewereover50%includedminocycline(852%),ticarcillin/clavulanate(815%),SMZco(742%),gatifloxacin(688%),cefoperazone/sulbactam(649%),ciprofloxacin(635%),pip
9、eracilli+tazobactam(630%),levofloxacin(569%).Conclusion:ThesedataindicatethatSMAisanimportantpathogenicbacteriumofbreathingmachine
10、associatedpneumoniafollowingcardiosurgeryofcardiopulmonarybypass.Itiseasytohappenatheartfailure,longtimecardiopulmonarybypassandmechanic
11、alventilation,complicatedMODS,mixedinfectionandusingcarbapenemantibioticsAfterinfection,littleantibioticscanbeselect
此文档下载收益归作者所有