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1、稽留流产相关因素分析中国妇幼健康研究2010年第2l卷第5期63l稽留流产相关因素分析王萍,李芳,甘露(陕西省妇幼保健院,陕西西安710003)[摘要]目的探讨稽留流产的相关因素,为采取有效干预措施提供理论依据.方法收集陕西省妇幼保健院妇保门诊的50例稽留流产患者(研究组)临床资料进行回顾性分析,同时选择要求终止妊娠的正常早孕患者48例作为对照组,所有研究对象均记录其基础资料和实验室检查结果.结果①两组基础资料比较无显着性差异(均P>0.05);②女性激素比较:研究组血清孕酮较对照组显着减低(t=6.54,P<
2、;0.05),血清睾酮较对照组显着升高(t=3.65,P<0.05),两组血清卵泡刺激素,黄体生成素,催乳素和雌二醇比较无显着性差异(均P>0.05);③免疫抗体和感染因素比较:研究组抗心磷脂抗体,抗子宫内膜抗体和抗人绒毛膜促性腺激素抗体阳性率较对照组显着升高(分别为l8.96,10.17,4.70,均P<0.05),抗精予抗体,抗卵巢抗体和抗透明带抗体阳性率比较无显着性差异(均P>0.05).研究组宫颈分泌物支原体和衣原体阳性率较对照组显着升高(分别为3.97,7.36,均P<0.05).
3、结论稽留流产与黄体功能不足,免疫和感染因素有关,患者需治疗病因后妊娠,以避免稽留流产再次发生.[关键词]稽留流产;女性激素;免疫抗体;感染因素doi:10.3969/j.issn.1673—5293.2010.05.024[中图分类号]R714.21[文献标识码]A[文章编号]1673—5293(2010)05—0631—03AninvestigationofrelatedfactorsofmissedabortionWANGPing,LIFang,GANLu(ShaanxiProvincialMaternalandCh
4、ildHealthHospital,ShaanxiXi'an710003,China)『Abstract『objectiveToinvestigaterelatedfactorsofmissedabortion.soastoprovidetheoreticalbasisfortakingeffectiveinterventions.MethodsTheclinicaldataof50womenwithmissedabortion(studygroup)and48normalearlypregnantwomenwhoreq
5、uestedtoterminatetheirpregnancy(controlgroup)inourmaternalhealthcareclinicwereanalyzedretrospectivelyandcompared.Thefundamentalinformationandlaboratoryresultsofallsubiectswererecorded.Results(!)Therewerenosignificentdifierencesinfundamentalinformationbetweenthetw
6、ogroups(P>0.05);(ThesernmlevelofPofwomenwithmissedabortionwassignificantlylowerthanthatofwomeninthecontrolgroup(t=6.54,P<0.05),whiletheserumlevelofTwassignificantlyhigherthanthatinthecontrolgroup(t=3.65,P<0.05).Therewasnosignificentdifferencesinserumleve
7、lsofFsH,LH,PRLandE,betweenthetwogroups(allP>0.05);③Thepositivedetectableratesofantieardiolipinantibody(ACLA).antiendometrialantibody(AEMA)andanti—hCGantibody(AhCGA)weresignificantlyhigherinthestudygroupcomparedwiththecontrolgroup(X2=18.96,10.17,4.70retrospecti
8、vely,al1P<0.05),whiletherewerenosignificentdifierencesinpositivedetectableratesofantispermantibody(ASA).antiovarianantibodies(A0A)andanti.zonapellucidaantib
