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时间:2020-06-06
《计算分辨率对调强放疗计划验证Gamma通过率的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、国际生物医学工程杂志2014年4月第37卷第2期IntJBiomedEng,April2014,Vo1.37,No.2·103··论著·计算分辨率对调强放疗计划验证Gamma通过率的影响张达光蒋胜鹏杨成文王伟【摘要】目的分析调强放疗计划面剂量验证过程中剂量计算的分辨率对Gamma通过率结果的影响,找出针对不同评判标准对应恰当的计算分辨率数值。方法选取25例调强放疗计划进行面剂量验证,对比分析采用2mm计算分辨率时,使用3mm/3%、2mm/2%和1mm/1%不同评判标准的Gamma通过率结果。采用0.5、1、3、
2、4、5mm不同的分辨率计算并输出面剂量分布,分别与使用Mapcheck测量到的该平面剂量分布进行Gamma通过率分析,对比分析采用不同计算分辨率得到的面剂量验证Gamma通过率结果。结果25例计划的225个射野的面剂量验证Gamma通过率均值随着计算分辨率的增大而降低。采用3mm/3%的评判标准时,计算分辨率为1mm的面剂量验证Gamma通过率为98.3%±1.3%,与分辨率为0.5mm的通过率98.3%±1.2%的数值很接近,其差异无统计学意义(0.05)。计算分辨率≥3mm的面剂量验证Gamma通过率相比于计
3、算分辨率为0.5mm的通过率均显著降低,其差异具有统计学意义(P<0.05)。采用2mm/2%的评判标准时,计算分辨率≥1nlm的面剂量验证Gamma通过率与计算分辨率为0.5mm的通过率相比均有显著下降,其箍异具有统计学意义(尸4、以保证验证结果的可靠性。【关键词】调强放疗计划验证;Gamma通过率;计算分辨率中图分类号:R730.55文献标识码:A文章编号:1673—4181(2014)02—0103—05ImpactofcalculationresolutiononGammapassrateforplanverificationofintensity-modulatedradiotherapyZhangDaguan~JiangShengpeng,YangChengwen,WangWei.NationalClinicalResearchC5、enterforCancer,CancerInstituteandHospitalofTianjinMedicalUniversity;KeyLaboratoryofCancerPreventionandTherapy,Tianjin30060,China【Abstract】0bjectiveToanalyzetheimpactofdosecalculationresolutiononGammapassrateforplanardosedistributionverificationofintensity—mod6、ulatedradiotherapy(IMRT),andtofindouttheappropriatecalculationresolutionvaluewithspecificappliedcriteria.Methods25IMRTplanswereselectedfortheplanardoseverification.TheGaromapassrateswith3mm/3%.2mm/2%and1mm/1%criteriawerecomparedandanalyzed.Theplanardosedistri7、butionswerecalculatedandexposedfromTPSwithdifierentresolutionsof0.5,1,2,3,4and5mm.ThepassratesofGammaanalysisbetweenthecomputeddosedistributionswithdifferentresolutionsandthedosedistributionsmeasuredbyMapcheckdevicewerecomparedandanalyzed.ResultsTheaverageGam8、mapassratesofallthe225fieldsdecreasedwiththeincrementofcalculationresolution.WhenthepassratesofGammaanalysiswerecalculatedusing3mm/3%criteria,thegammapassratewith1innand0.5mmcalculationre
4、以保证验证结果的可靠性。【关键词】调强放疗计划验证;Gamma通过率;计算分辨率中图分类号:R730.55文献标识码:A文章编号:1673—4181(2014)02—0103—05ImpactofcalculationresolutiononGammapassrateforplanverificationofintensity-modulatedradiotherapyZhangDaguan~JiangShengpeng,YangChengwen,WangWei.NationalClinicalResearchC
5、enterforCancer,CancerInstituteandHospitalofTianjinMedicalUniversity;KeyLaboratoryofCancerPreventionandTherapy,Tianjin30060,China【Abstract】0bjectiveToanalyzetheimpactofdosecalculationresolutiononGammapassrateforplanardosedistributionverificationofintensity—mod
6、ulatedradiotherapy(IMRT),andtofindouttheappropriatecalculationresolutionvaluewithspecificappliedcriteria.Methods25IMRTplanswereselectedfortheplanardoseverification.TheGaromapassrateswith3mm/3%.2mm/2%and1mm/1%criteriawerecomparedandanalyzed.Theplanardosedistri
7、butionswerecalculatedandexposedfromTPSwithdifierentresolutionsof0.5,1,2,3,4and5mm.ThepassratesofGammaanalysisbetweenthecomputeddosedistributionswithdifferentresolutionsandthedosedistributionsmeasuredbyMapcheckdevicewerecomparedandanalyzed.ResultsTheaverageGam
8、mapassratesofallthe225fieldsdecreasedwiththeincrementofcalculationresolution.WhenthepassratesofGammaanalysiswerecalculatedusing3mm/3%criteria,thegammapassratewith1innand0.5mmcalculationre
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