调肝理脾法治疗腹泻型肠易激综合征症状疗效观察.pdf

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1、世界中医药2015年5月第10卷第5期调肝理脾法治疗腹泻型肠易激综合征症状疗效观察汪正芳张声生(首都医科大学附属北京中医医院消化中心，北京，100010)摘要目的：观察调肝理脾法治疗腹泻型肠易激综合征(IBS—D)的临床疗效。方法：97例IBS—D患者随机分为调肝理脾中药组和匹维溴铵西药纽，分别给予调肝理脾方及匹维溴铵治疗。疗程均为4周，疗程结束后随访3个月，观察症状疗效。结果：治疗2周后、治疗4周后、治疗结束后第1个月及第3个月随访时，2组总症状积分改善明显优于治疗前，差异有统计学意义(P<0．05)；治疗4周后，2组

2、病例IBS症状积分减少值，调肝理脾组优于匹维溴铵纽，差异有统计学意义(P

3、withDiarrhea(mS-D)byRegulatingLiverandSpleenWangZhengfang，ZhangShengsheng(Digestioncenter，BeijingTCMHospitalAffiliatedToCapitalMedicalUniversity，Beijing100010，China)AbstractObjective：Toobservetheclinicaleficacyofthemethodofregulatingliverandspleenontreatingirrita

4、blebowelsyn-dromeofdiarrheapattern．Methods：Atotalof97IBS—Dpatientswererandomlydividedintotwogroups．Onegroupreceivedtradi-tionalChinesemedicinetreatmentwhichhaseffectofregulatingliverandspleen；andtheothergroupreceivedpinaveriumbro—mide．Bothgroupsreceivedthetreatme

5、ntfor4weeks．Wefollowedupthepatientsfor3monthsaftertreatmenttoobservethesymptomsandthecurativeeffect．Results：Thesymptomsofbothgroupsshowedobviousimprovementthanbeforethetreatmentwhenitwasobservedafter2weeksand4weeksoftreatment。andlmonthand3monthsaftertreatment．The

6、rewerestatisticaldifferences(P<0．05)．After4weeksoftreatment，thesymptomreductionvalueofregulatingliverandspleengroupwasbetterthanthatofpinaveriumbromidegroupwithstatisticallysignificantdifference(P<0．05)；thetotaleffectivenessoftheregulatingliverandspleengroupwas92

7、．2％andpinaveriumbromidegroupwas69．6％．itindicatedthatregulatingliverandspleengroupwasbetterthanthepinaveriumbromidegroupandthedifferencewasstatisticallysignificant(P<0．05)．Intherespectofimpro—ringthemajorsymptomssuchasthenumberofdefecationandcharacterofstool，there

8、gulatingliverandspleengroupwassuperiorthanpinaveriumbromidegroup，andthedifferencewasstatisticallysignificant(P<0．05)．Conclusion：Theprescriptionofregn—latingliv