能谱CT对肺组织含血量测定的研究及初步应用-论文.pdf

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1、胸部影像学CHESTlMAGING227能谱CT对肺组织含血量测定的研究及初步应用何沂峰王新文。李天平王晴柔张琰琰迟婧蒋梅花陈克敏【摘要】目的：探讨宝石cT能谱成像(gemstonespectralimaging，GSI)物质分离技术(materialdecomposition，MD)对肺血液循环定量分析的价值。方法：运用GSI对37例患者进行CT扫描，所得图像通过能谱分析软件(GSIviewer)对肺组织含血量进行定量分析。采用t检验方法进行统计学分析。结果：平扫血基图上双肺前部血基值低于后部，差异有统计学意义(尸<0．05)，碘基图上前、后部碘基值差异无统计学意义(p=0．785

2、)I增强前后血基值无统计学差异(p=0．627)；右肺下叶血基值分别高于同侧上叶和中叶，差异有统计学意义(尸<0．05)，左肺下叶比同侧上叶血基值高，差异有统计学意义(尸<0．05)，外周与肺门区血基值差异无统计学意义(P=0．701)。结论：GSI物质分离技术可对肺组织含血量进行定量分析，并可初步运用该技术，探究人体肺组织血液分布特点。【关键词】宝石CT能谱成像，物质分离；定量；肺血含量中图分类号：R445．3文献标志码：A文章编号：10065741(2014)-03—0227—04StudyofGemstoneSpectralImaginginQuantitativeAnalys

3、isofPulmonaryBloodDensityHEYi—feng。，WANGXin—wen。，LITian—ping。，WANGQing—rou，ZHANGYah—yanCHIJing，JIANGMei—hua，CHENKe—min【Abstract】Purpose：Gemstonespectralimaging(GSI)hastheabilityofmaterialdecomposition(MD)forseparatingmaterialsandanalyzingthecontentofcertainmaterials．Thepurposeofthisstudywastoev

4、aluatetheroleofGSIinthequantitativeanalysisofthelungcirculation．Methods：GS1wasperformedin37patients．DatawereprocessedonGSIViewerbrowsertoanalyzethepulmonaryblooddensity．Thendatawasanalyzedstatisticallybyt-testmethods．Resuits：Intheblood-basedMDimages，theanteriorblooddensityofthelungwaslowerthant

5、heposterior．anditindicatedastatisticalsignificantdifference(尸<0．05)，whereastherewasnostatisticaldifferenceintherelativeiodinedensitybetweentheanteriorandtheposteriorlung(尸=0．785)．Andthedifferenceinthepulmonaryblooddensitybetweenpre—contrastandpost-contrastwaswithnostatistica1significant(P=0．627

6、)．Theblooddensityintheinferiorlobeofrightlungwashigherthantheipsilateralsuperiorandmiddlelobes，andtheblooddensityintheinferiorlobeofleftlungwashigherthantheipsilateralsuperiorlobe，thedifferenceswerewithstatisticalsignificant<0．05)．Therewasnostatisticaldifferencebetweentheblooddensityoftheperiph

7、eralregionandthehilarregionI_O．701)．Conclusion：TheMDmethodofGSIcanperformthequantitativeassessmentofthelungblooddensity，anditcanbepreliminarilyusedininvestigatingthecharacteristicofpulmonaryblooddistribution．【Keywords】Gemstonespec