能谱CT估算原发性肝癌其血供比例的初步研究.pdf

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1、·ll98·临床放射学杂志2014年第33卷第8期腹部放射学能谱CT估算原发性肝癌其血供比例的初步研究高永广，郝敬明，李光超，赵宝忠，师毅冰，王涛，夏萍，陈刚【摘要】目的利用能谱cT(碘基图)对肝癌患者及正常人群进行测量，估算不同病变其血供比例，并对其进行分析。方法对22例原发性肝癌进行分析，20名正常人群作为对照组，测得病变动脉期及静脉期碘含量数值，并得出肝动脉期与静脉期百分比进行统计学分析，同时对肝癌患者依据Child—Pugh分级进行分组，并与正常人群进行方差分析。结果利用正常肝脏及肝癌血供比例进行比较，得出两组数据之

2、间差异具有统计学意义(t值=25．34，P<0．05)，正常人群及Child．Pugh分级对多组均数进行方差分析(F值=15．58)，Child—Pugh组别较正常人群差异具有统计学意义(P值分别为0．007、0．000、0．000)，Child—PughA组较Child．PughB组及C组差异亦具有统计学意义(尸值分别为0．008、0．009)，但Child—PughB组与Child—PughC组之间差异无统计学意义(P=0．316)。结论利用能谱CT测量其动脉期及静脉期碘含量之比，可以估算出肝癌其血供比例较正常肝组织血供

3、比例发生改变，从而更简便地发现肝癌其血供比例的改变。【关键词】能谱肝脏体层摄影术，x线计算机EnergySpectralCTScansforEstimationofHepaticArteryIndexofLiverCancer：APreliminaryStudyGAOYongguang，HAOJingming，LIGuangchao，eta1．DepartmentofRadiology，XuzhouMunicipalCentralHospital，Xuzhou，JiangsuProvince221000，P．R．China【

4、Abstract】ObjectiveToestimatetheproportionofhepaticbloodsupplyinnormalsubjectsandinpatientswithlivercancerbyusingenergyspectralCT(iodinefigure)．MethodsAtotalof22patientswithprimarylivercancer(studygroup)and20healthysubjects(controlgroup)wereenrolledinthisstudy．Theio

5、dinevalueswithinthelesionsinarterialandvenousphaseweredetermined，andthepercentageofbloodflowinhepaticarterialphaseandvenousphasewerethusobtained．Theresultswerestatisticallyanalyzed．AccordingtoChild—Pughcriterion，thepatientsweredividedintodifferentgroups．Theresultsw

6、erecomparedwithnormalpopulationbyusingvarianceanalysis．ResultsStatisticallysignificantdifferencesinthebloodsupplyexistedbetweennormallivertissueandlivercancer(t=25．34，P<0．05)．Varianceanal—ysisshowedthatthebloodsupplyinnormalpopulationwassignificantlydifferentwithCh

7、ild—Pu【ghgroup(P=0．007，P=0．007andP=0．000respectively1．SignificantdiferencesinthebloodsupplyexistedbetweenChild-PughAandChild-PughBaswellasbetweenChild—PughAandChild—Pu【ghC(P=0．008，P=0．009respectively)，whilethedifferencebetweenChild—PughBandChild—PughCwasnotsignific

8、ant(P=0．316)．ConclusionIodinecontentinthetissuewhichismeasuredbyenergyspectralCTcanestimatethebloodsupplyinthetissue．Thistechniquecanestimatetheb