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时间:2020-04-22
《氟哌噻吨美利曲辛联合盐酸替扎尼定治疗肌紧张性头痛的观察-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·188·盛堑医学院学塑生篁9卷第2期JournalofChengduMedicalCollege,2014,Vo1.9,No.2网络出版地址:http://www.enki.net/kcms/detail/51.1705.R.20140417.1420.004.htmldoi:10.3969/j.issn.1674—2257.2014.02.022临床报道·氟哌噻吨美利曲辛联合盐酸替扎尼定治疗肌紧张性头痛的观察王博(河北省唐山市遵化市人民医院神经内科,唐山064200)【摘要】目的研究氟哌噻吨美利曲辛联合盐酸替扎尼定治疗肌紧张性头痛的临床
2、疗效。方法将2011年1月~2012年12月期间我院门诊收治的肌紧张性头痛患者130例纳入研究,随机分为给予氟哌噻吨美利曲辛联合盐酸替扎尼定治疗的观察组(65例)和单独给予盐酸替扎尼定治疗的对照组(65例),观察治疗前后的头痛程度、负面情绪及生活质量。结果治疗后两组患者头痛程度及负面情绪评分明显低于治疗前,生活质量明显高于治疗前;观察组患者的疼痛数字量表(NRS)评分为(1.3±0.2)分、汉密尔顿焦虑量表(HAMA)评分为(13.8±1.6)分、汉密尔顿抑郁量表(HAMD)评分为(14.3±2.2)分、焦虑自评量表(SAS)评分为(47.
3、5±6.3)分、抑郁自评量表(SDS)评分为(48.8±4.5)分,均明显低于对照组;观察组躯体功能(74.1±9.6)分、心理功能(59.1±5.7)分、社会功能(57.8±2.74)分、认知功能(58.4±5.7)分、总体生活质量(81.8±8.3)分,均明显高于对照组(P4、upentixolMelitracenCombinatedwithTizanidineHydrochlorideintheTreatmentofmuscleTensionHeadacheWANGBo(DepartmentofNeurology,ZunhuaPeopleSHospital,Tangshan064200,China)[Abstract]0bjectiveTostudytheclinicalefficacyofflupentixolmelitracencombinatedwithtizanidinehydrochlorideint5、hetreatmentofmuscletensionheadache.MethodsPatientswithmusculartensionheadachefromJanuary2011toDecember2012inourhospitalwereincludedinthestudy.Patientswererandomlydividedintoobservationgroupreceivedflupentixolmelitracencombinatedwithtizanidinehydrochlorideandcontrolgrouprec6、eivedtizanidinehydrochloridetherapy,theextentofheadaches,negativeemotionsandqualityoflifebeforeandaftertreatmentswerecompared.ResultsAftertreatment,patients'degreeofheadacheandnegativeemotionsscorewassignificantlylowerthanbeforetreatmentintwogroups,thequalityoflifewassigni7、ficantlyhigherthanbeforetreatments.NRSwas(1.3±0.2)points,HAMAwas(13.8-2_-1.6)points,HAMDwas(14.3±2.2)points,SASwas(47.54-6.3)points,andSDSwas(48.8±4.5)pointsintheobservationgrouppatients.whichweresignificantlylowerthanthoseinthecontrolgroup.Physicalfunctionwas(74.1±9.6)poi8、nts,psychologicalfunctioningwas(59.1±5.7)points,socialfunctioningwas(57.8±2.74)points,cog
4、upentixolMelitracenCombinatedwithTizanidineHydrochlorideintheTreatmentofmuscleTensionHeadacheWANGBo(DepartmentofNeurology,ZunhuaPeopleSHospital,Tangshan064200,China)[Abstract]0bjectiveTostudytheclinicalefficacyofflupentixolmelitracencombinatedwithtizanidinehydrochlorideint
5、hetreatmentofmuscletensionheadache.MethodsPatientswithmusculartensionheadachefromJanuary2011toDecember2012inourhospitalwereincludedinthestudy.Patientswererandomlydividedintoobservationgroupreceivedflupentixolmelitracencombinatedwithtizanidinehydrochlorideandcontrolgrouprec
6、eivedtizanidinehydrochloridetherapy,theextentofheadaches,negativeemotionsandqualityoflifebeforeandaftertreatmentswerecompared.ResultsAftertreatment,patients'degreeofheadacheandnegativeemotionsscorewassignificantlylowerthanbeforetreatmentintwogroups,thequalityoflifewassigni
7、ficantlyhigherthanbeforetreatments.NRSwas(1.3±0.2)points,HAMAwas(13.8-2_-1.6)points,HAMDwas(14.3±2.2)points,SASwas(47.54-6.3)points,andSDSwas(48.8±4.5)pointsintheobservationgrouppatients.whichweresignificantlylowerthanthoseinthecontrolgroup.Physicalfunctionwas(74.1±9.6)poi
8、nts,psychologicalfunctioningwas(59.1±5.7)points,socialfunctioningwas(57.8±2.74)points,cog
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