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时间:2017-12-07
《某医院1999-2008年临床分离细菌种群分布与变迁》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·196·坚国感染控制杂志2010年5月第9卷第3期ChinJInfectControlVol9No3May2010.实验研究.某医院1999-2008年临床分离细菌种群分布与变迁孔繁林,储从家,管新龙,李杰芬,杨宇溪(玉溪市人民医院,云南玉溪653100)[摘要]目的了解某院近10年来临床分离细菌的菌群分布和变迁情况。方法对该院1999年1月一2【)08年12月间住院和门诊就诊患者送检的60846份临床标本(血液、尿液、咽拭子、痰、大便、阴道拭子和无菌体液)细菌培养结果作回顾性分析。结果10年共分离临床细
2、菌67属207种18674株,细菌分离率30.69%(18674/60846),革兰阴性杆菌、革兰阳性球菌与真菌的比例为54.42:32.21:11.56。前6位优势菌群分别是甲型副伤寒沙门菌、草绿色链球菌群、大肠埃希菌、酵母样真菌、凝固酶阴性葡萄球菌和金黄色葡萄球菌。革兰阴性杆菌比例明显上升,条件致病菌检出增多,草绿色链球菌群、肠道致病菌和甲型副伤寒沙门菌的检出则下降(P3、件致病菌;变迁[中图分类号]R378[文献标识码]A[文章编号]1671—9638(2010)()3—0196—04Distributionandchangeofmicrobialpopulationofclinicalisolatedbacte—riafromahospitalbetween1999and2008KONGFan—lin,CHUCong-jia,GUANXin—long,LIJie—fe札,YANGYu-xi(YuxiPeople'sHospital,Yuxi653100,China)[Ab4、stract]ObjectiveTostudythedistributionandchangeofmicrobialpopulationofclinicalisolatedbacteriafromahospita1inrecent10years.MethodsBacteria1cultureresultsof60846clinicalsamples(blood,urine,throatswab,sputum,stool,vaginaswab,andsterilebodyfluid)frominpatient5、sandoutpatientsbetweenJanuary,1999andDecember,2008wereanalysedretrospectively.ResultsTheseisolatesincluded67genus207species18674strainsofbacteria,theisolationratewas30.69(18674/60846),theratioofgram-negativebacillustogram-positiveCOCCUSandfunguswas54.42:326、.21:11.56.ThemajorbacteriawereSalmonellaparatyhiA,Ⅵ一ridansstreptococci,Escherichiacoli,yeast-likefungi,coagulasenegativeS£以户^0c0ff“andStaphylococcusau—reus.Theproportionofgram-negativebacillusroseobviously,SOdidtheopportunisticpathogens.Theisolationratesof7、ViridansstreptococcusandentericpathogensandSalmonellaparatyhiAdecreased(P<0.O1).ConclusionChangeinflora1isinaccordancewithfundamentalcharacteristicsofpresentdayinfection;Theincreaseofoppor—tunisticpathogensisdisadvantageoustothepreventionandtreatmentofmult8、ipleinfectiousdiseases.EKeywords]bacteria;pathogen;floradistribution;opportunisticpathogen;changelChinInfectContro1,2010,9(3):196—199】临床细菌种群结构的分布和变迁对了解感染性疾病的病原属性、细菌耐药变迁、流行病学发展趋势1材料与方法以及疾病的防治等都具有十分重要的意义。笔者对某院近
3、件致病菌;变迁[中图分类号]R378[文献标识码]A[文章编号]1671—9638(2010)()3—0196—04Distributionandchangeofmicrobialpopulationofclinicalisolatedbacte—riafromahospitalbetween1999and2008KONGFan—lin,CHUCong-jia,GUANXin—long,LIJie—fe札,YANGYu-xi(YuxiPeople'sHospital,Yuxi653100,China)[Ab
4、stract]ObjectiveTostudythedistributionandchangeofmicrobialpopulationofclinicalisolatedbacteriafromahospita1inrecent10years.MethodsBacteria1cultureresultsof60846clinicalsamples(blood,urine,throatswab,sputum,stool,vaginaswab,andsterilebodyfluid)frominpatient
5、sandoutpatientsbetweenJanuary,1999andDecember,2008wereanalysedretrospectively.ResultsTheseisolatesincluded67genus207species18674strainsofbacteria,theisolationratewas30.69(18674/60846),theratioofgram-negativebacillustogram-positiveCOCCUSandfunguswas54.42:32
6、.21:11.56.ThemajorbacteriawereSalmonellaparatyhiA,Ⅵ一ridansstreptococci,Escherichiacoli,yeast-likefungi,coagulasenegativeS£以户^0c0ff“andStaphylococcusau—reus.Theproportionofgram-negativebacillusroseobviously,SOdidtheopportunisticpathogens.Theisolationratesof
7、ViridansstreptococcusandentericpathogensandSalmonellaparatyhiAdecreased(P<0.O1).ConclusionChangeinflora1isinaccordancewithfundamentalcharacteristicsofpresentdayinfection;Theincreaseofoppor—tunisticpathogensisdisadvantageoustothepreventionandtreatmentofmult
8、ipleinfectiousdiseases.EKeywords]bacteria;pathogen;floradistribution;opportunisticpathogen;changelChinInfectContro1,2010,9(3):196—199】临床细菌种群结构的分布和变迁对了解感染性疾病的病原属性、细菌耐药变迁、流行病学发展趋势1材料与方法以及疾病的防治等都具有十分重要的意义。笔者对某院近
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