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1、PREVENTIVEVETERINARYMEDICINEPreventiveVeterinaryMedicine25(1995)51-62RiskfactorsassociatedwithseropositivitytoporcinerespiratorycoronavirusinDanishswineherdsJ.Flori,,J.Mousing**,I.Gardnerb,P.Willeberg,P.Haved“FederationofDanishPigProducersandSlaughterhou
2、ses.Axelborg,Axeltorv3,DK-1609CopenhagenV,DenmarkbDepart,mentofMedicineandEpidemiology,SchoolofVeterinaryMedicine,UniversityofCalifornia,Davis,CA95616.USA‘DivisionofEthologyandHealth,RoyalVeterinaryandAgriculturalUniversity,Biilowsvej13,DK-1870Frederiksb
3、ergC,Denmark?TtateVeterinaryInstituteforVirusResearch,Lindholm,DK-4771Kalvehave,DenmarkAccepted8April1995AbstractSerolo,Eicalscreeningofswineherdsin1984indicatedthatporcinerespiratorycoronavirus(PRCV)hadbeenintroducedintoDenmark.Todetermineriskfactorsass
4、ociatedwiththeintroductionofPRCV,across-sectionalstudyof408DanishswineherdswascarriedoutbetweenMay1985andJune1986.Theassociationbetweenherd-PRCVserologicalstatusandpossibleriskfactors,obtainedfromafieldquestionnaire,wasassessedbyunconditionalmaximumlikel
5、ihoodlogisticregression.Anincreasingherdsize,locationintheJutlandpeninsula(comparedwithlocationontheislandofFunen)(OR=7.9inamultivariablelogisticregressionmodelnotincludinginteractionterms),thepresenceofaslurrysystem(i.e.pigslivingonaslattedfloor)(OR=4.6
6、)andpurchaseofpigs(OR=1.7)weresignificantly(P<0.05)associatedwithseropositivity.Twosignificantinteractions,bothinvolv-ingherds#ize,weresubsequentlyidentified.ThePF!CVserologicalstatusofneighbouringherdswasfoundtoberelated,andclosenessofaseropositiveherdw
7、asassociatedwithanincreasedriskofaherdbeingserologicallypositive.There.sultsofthisstudyindicatethatherdsizemaybeanimportantdeterminantofairbornetransmissionofPRCVinfection,andthatherdsizemaymodifytheeffectofotherriskfactors.Keywords:PRCV;Riskfactors;Airb
8、orneinfections*Correspondingauthor.0167-5877/95/$09.5001995ElsevierScienceB.V.AllrightsreservedSSDI016?-5877(95)00498-Xs2J.Florietal./PreventiveVeterinnryMedicine25(1995)51421.IntroductionPorcinerespiratorycoronavirus(PRCV