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ID:44308652
大小:62.00 KB
页数:6页
时间:2019-10-20
《血浆脑钠肽水平在心房纤颤患者中的临床价值》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、血浆脑钠肽水平在心房纤颤患者中的临床价值血浆脑钠肽水平在心房纤颤患者中的临床价值【摘要】目的:分析血浆脑钠肽(BNP)水平在心房纤颤患者复律前、后中的变化,评价其临床应用价值。方法:选取2010年12月-2013年12月本院确诊为心房纤颤且成功复律的57例患者作为观察组,依据发作时间分为两亚组:阵发性房颤(发作时间〈2d)31例,持续性房颤(持续发作2d〜12个月)26例;选取同期在本院行健康检查止常者33例作为对照组,分析观察组复律前后的血浆BNP水平变化。结果:观察组复律前的血浆BNP比对照组高,比较差异有统计学意义(P<0.05);观察组两亚组的3项指标水平组间比较
2、,差异差异有统计学意义(P〈0・05);观察组患者的BNP水平与LEVF呈负相关性,与LVEDD呈正相关性,比较差异有统计学意义(P<0.05);观察组复律后、房颤复发患者的血浆BNP水平比对照组高,差异有统计学意义(P<0.05);窦律维持患者的血浆BNP水平与对照组比较,差异无统计学意义(P>0・05)。结论:心房纤颤患者复律前血浆脑钠肽水平明显升高,复律后其显著下降,可用于评价房颤患者的发作时间和治疗预后效果。【关键词】血浆脑钠肽;心房纤颤;相关性[Abstract】Objective:Toanalyzethechangeofplasmabrainnatriuret
3、icpeptide(BNP)levelsinpatientswithatrialfibrillationbeforeandaftercardioversion,andevaluateitsclinicalapplicationvalue.Method:57casesdiagnosedwithatrialfibrillationandsuccessfulcardioversionofpatientsfrom2010Decemberto2013Decemberinourhospitalwereselectedasobservationgroup,accordingtotheo
4、nsettimetheyweredividedintotwosubgroups:31caseswithparoxysmalatrialfibrillation(timeofonset<2days)and26caseswithpersistentatrialfibrillation(continuedtoattack2days~12months)33casesinourhospitalforhealthexaminationfornormalinthesameperiodwereselectedascontrolgroup,thechangesofplasmaBNPleve
5、lsbeforeandaftercardioversionwereanalyzedandobserved・Result:TheplasmaBNPoftheobservationgroupwashigherthanthatofthecontrolgroupbeforethecardioversion,thedifferencewassignificant(P<0.05);threeindexesofthetwosubgroupsandtheobservationgroupwerecomparedbetweengroups,thedifferencewassignifican
6、t(P<0.05);thelevelofBNPoftheobservationgroupshowednegativecorrelationtoLEVF,andshowedpositivecorrelationtoLVEDD,thedifferencewassignificant(P<0.05).Aftercardioversion,theBNPlevelofthepatientsforatrialfibrillationrecurrenceoftheobservationgroupwashigherthanthatofthecontrolgroup,thedifferen
7、cewassignificant(P<0.05)・BNPlevelofpatientswiththemaintenanceofsinusrhythmhadnosignificantdifferencefromthatofthecontrolgroup(P>0.05)・Conclusion:Theplasmabrainnatriureticpeptidelevelsofpatientswithatrialfibrillationincreasebeforecardioversionanddecreasesignificantly
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