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1、~APPLIEDCATALYSISA:GENERALELSEVIERAppliedCatalysisA:General152(1997)143-151Hydrogenationofpyrrolederivatives.PartIV.Hydrogenationof1-methylpyrrole--a*Lfiszl6Hegedus',TiborMfith~b,AntalTunglercaDepartmentofOrganicChemicalTechnology,TechnicalUniversityofBudapest,MffegyetemP.O.Box91,H-I521Bu
2、dapest,HungarybResearchGroupforOrganicChemicalTechnology,HungarianAcademyofSciences,TechnicalUniversityofBudapest,MffegyetemP.O.Box91,tt-1521Budapest,HungaryCDepartmentofChemicalTechnology,TechnicalUniversityofBudapest,MgegyetemP.O.Box91,H-1521Budapest,HungaryReceived18July1996;revised5Oc
3、tober1996;accepted17October1996AbstractTheheterogeneouscatalytichydrogenationof1-methylpyrrolewasinvestigatedinnon-acidicmedium.Varioussupportednoblemetalcatalystsandsolventshavebeenscreened.Thehighestactivitieswereprovidedbyrhodiumandrutheniumcatalysts.Inpalladiummediatedhydrogena-tionst
4、heactivityofthecatalystwasincreasedbyappropriatesolvents.Thereactivityof1-methylpyrrolewascomparedwiththatofpyrroleanditsderivativeshydrogenatedpreviously.Keywords:Heterogeneouscatalytichydrogenation;1-Methylpyrrolidine;1-Methyl-pyrrole;Palladiumcatalyst;Rhodiumcatalyst;RutheniumcatalystI
5、.IntroductionPyrroleanditsderivativesareconsideredtobethestrongestcatalystpoisonamongheterocycliccompoundscontainingnitrogen.ThepoisoningcausedbysecondaryortertiaryNatomswasgenerallyeliminatedbyusingproticacids[1].Previouslywereportedtheheterogeneouscatalytichydrogenationsoftwopyrrolederi
6、vatives(1-methyl-2-pyrrole-ethanolandmethyll-methyl-2-pyrrole-acetate)innon-acidicmedium,overdifferentsupportednoblemetalcatalysts[2--41.*Correspondingauthor.Tel.:(+36-1)4631261;fax:(+36-1)4633648;e-mail:hegedus@ch.bme.hu0926-860X/97/$17.00Copyright©1997ElsevierScienceB.V.Allrightsreserve
7、d.PIIS0926-860X(96)00359-6144L.Hegedffsetal./AppliedCatalysisA:General152(1997)143-151Catalyst,Solvent(s)ICH312Scheme1.Inthisworktheheterogeneouscatalytichydrogenationof1-methylpyrrole(1)to1-methylpyrrolidine(2)wasinvestigated(Scheme1),inordertocomparethereactivityo
