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ID:39107246
大小:4.10 MB
页数:27页
时间:2019-06-25
《OMOM+pH胶囊监测非糜烂性反流病的初步临床分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、重庆压科大学磺士研究生学位论文ANINITIALCLINICALSTUDYoFNoNERoSIVEREFLUXDISEASEPATIENTSMONITOREDBYOMOMPHCAPSULEABSTRACTOBJECTIVES:Gastroesophagealrefluxdiseaseisacommonchronicrecurrentepisodesofupperdigestivesystemdiseases,andesophagealpHmonitoringisanimportantmeansofdiagnosisofgastroesophagealrefluxd
2、isease.TraditionalcatheterpHmonitoringneedtoretainnasalcatheter,andmaymakethepatientdiscomfortandinconvenience,butwirelessesophagealpHcapsuletoovercometheshortcomingsofthetraditionalcatheterpHmonitoring.Theaimofthisstudywastoinvestigatethesafety,reliability,andcomplicationsrelatedtodo
3、mesticOMOMpHcapsulemonitoringinnon—erosiverefluxdisease,andtoevaluateitspracticalvalueinclinicalapplications.METHODS:Patientswithsymptomsofreflux,gastroesophagealrefluxdiseasequestionnaire(GerdQratings)morethan10pointsandnegativeendoscopywereincludedingastroenterologyoutpatientofourho
4、spital.OMOMpHcapsulewaspositionedtransorally5cmabovethedentatelineusingendoscopicmeasurementfor48—96hoursesophagealpHmonitoring.ThepHdatawereuploadedtoacomputerforanalysisof4combiningmanualandautomatic.ThepatientswereobservedcomplicationsrelatedtothewirelesspHcapsuleduringmonitoringpr
5、ocess.Theyansweredaquestionnaire,whichdescribedthetoleranceandsatisfactionduringthepHtests.RESULTS:Atotalof25patients(7menand31women)wereenrolledandthemeanagewas48.2+10.1years.Theaveragedurationformonitoringwas77:22+18:45(42:31—105:55).ThemeantimeofpHcapsuleexcretedwiththestoolwas(6.4
6、+2.88)days.DuringpHcapsulemonitoring,14(56%)patientshadabnormalacidexposureand11(44%)patientshadnormalacidexposure.ProblemsofTechnicalfailuresoccurredsuchas9(36%)datainterruption,2(8%)dislodgementand2(8%)capsuleremoval.Symptomsrelatedtocapsuleattachmentwere:asymptomaticin8(32%),mildsy
7、mptomsin10(40%),moderatesymptomstoendurein4(16%),andseveresymptomsCannotstandthethreecases(12%),andtwopatients(8%)requiredremovalofthecapsule.CONCLUSION:OMOMpHcapsuleisasafeandreliablemethod,whichisaverypromisingtechnologyandhasacertainclinicalvalue,butneedstobefurthertechnicalimprove
8、ments
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