《天然药化课件英》PPT课件

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1、NaturalProductsChemistry唐万侠(TangWanxia)2012-2013(2)BilingualTeachingMethodsExplaintheknowledgeinEnglishandChinese.Payattentiontothecultureexchangeintheworld.ImprovetheabilitytoutilizespecialtyEnglish.ExaminationforNaturalProductsChemistrySelectiveCourse1.Cometotheclassontime:102.Behavi

2、ourinclass:103.Classnote:104.Examinationattheendoftheclass:70Note:Someonecan’tbeallowedtocometotheexaminationifheisabsentfromtheclassmorethan6times.ClassContentsChapter1IntroductionChapter2SaccharideandGlycosidesChapter3PhenylpropanoidsChapter4QuinonesChapter5FlavonoidsChapter6Terpen

3、oidsandVolatileoilsChapter7TriterpenoidsandSaponinsChapter8SteroidesandGlycosidesChapter9AlkaloidsChapter10MarineNaturalProducts糖和苷苯丙素类化合物醌类化合物黄酮类化合物萜类和挥发油三萜及其苷类甾体及其苷类生物碱海洋天然药物1、Outline3、Extractandisolationmethods4、Structuralelucidationmethods2、BiosynthesisChapter1Introduction1、OutlineD

4、efinition:Naturalproductschemistryisasubjecttoresearchthechemicalconstituentsofnaturalmedicinalplantsonthebaseofmodernscientifictheoryandmethods.Contents：Structuralcharacteristics,physicochemicalproperties,extractandisolationmethods,andstructuralelucidationofthechemicalconstituentsofall

5、kindsofnaturalmedicinalplants.Researchresource:Naturalplants(major),animals,minerals,andmicroorganism.1、OutlineNaturalmedicinalplantsherbmedicine麻黄(Ephedraspp.)1、Outline1、Outline槐花米（Sophorajaponica）1、Outline1、OutlineDevelopmentsinforeigncountries●In1769,tartar(potassiumhydrogentartrate)

6、wastransferredtocalciumsaltanddecomposedinsulphuricacidtoproducetartaricacid.(K.W.Schelle,Swedish)●In1804,morphinewasisolatedfromopium(Dorosine,French)●In1806,morphinewasisolatedfromopium(Serturner,German)●In1810-1860,theperiodofalkaloiddevelopment1、OutlineSpectroscopicanalysis:NMR,MS,I

7、R,andUV.Researchmethods:extractandisolationguidedbybioactivescanning,structuralmodification,andtotalsynthesis.1、OutlineDevelopmentofnowadays1、Outline3、Extractandisolationmethods4、Structuralelucidationmethods2、BiosynthesisChapter1Introduction2、BiosynthesisCO2H2O葡萄糖代谢磷酸烯醇式丙酮酸丙酮酸乙