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1、江西医药2012年5月第47卷第5期JiangxiMedicalJournal，May2012，Vol47，No5·427·[20]。这些研究提示阿利吉仑可能比传统的ACE抑[10]KimS,IwaoH.Molecularandcellularmechanismsofangiotensin制剂和ARB更能抑制RAS活性，尤其是在组织水II-mediatedcardiovascularandrenaldiseases.PharmacolRev,2000,52(1):11.平和细胞水平。[11]DanserAH,Ko
2、ningMM,AdmiraalPJ,etal.Metabolismofan鄄因此，阿利吉仑这些与传统RAS系统阻断剂giotensinIbydifferenttissuesintheintactanimal.AmJPhysiol,的不同点可能给临床治疗带来新的机会。1992,263:H418.参考文献[12]AldermanMH.Plasmareninactivityandcoronaryheartdisease:[1]DongYF,LiuL,KataokaK,etal.Aliskirenpreventscard
3、iovascu鄄aretheyrelated?CurrOpinNephrolHypertens,1995,4(2):201.larcomplicationsandpancreaticinjuryinamousemodelofobesi鄄[13]MuhlesteinJB,MayHT,BairTL,etal.Relationofelevatedplas鄄tyandtype2diabetes.Diabetologia,2010,53(1):180.mareninactivityatbaselinetocardiacev
4、entsinpatientswithan鄄[2]DongYF,KataokaK,ToyamaK,etal.Attenuationofbraindamagegiographicallyprovencoronaryarterydisease.AmJCardiol,106andcognitiveimpairmentbydirectRenininhibitioninmicewith(6):764.chroniccerebralhypoperfusion.Hypertension,2011,58(4):635.[14]Ta
5、ylorAAAD,AroraV.Reninsystemsuppressionwiththeoral[3]YamamotoE,KataokaK,DongYF,etal.Aliskirenenhancesthedirectrenininhibitoraliskirenadministeredaloneorincombina鄄protectiveeffectsofvalsartanagainstcardiovascularandrenalin鄄tion:apooledanalysisof1093patientswith
6、hypertension.JAmjuryinendothelialnitricoxidesynthase-deficientmice.Hyperten鄄CollCardiol,2007,49(SupplA):370A.sion,2009,54(3):633.[15]FeldtS,MaschkeU,DechendR,etal.Theputative(pro)reninre鄄[4]DongYF,LiuL,LaiZF,etal.Aliskirenenhancesprotectiveeffectsceptorblocke
7、rHRPfailstoprevent(pro)reninsignaling.JAmSocofvalsartanagainsttype2diabeticnephropathyinmice.JHyper鄄Nephrol,2008,19(4):743.tens,2010,28(7):1554.[16]HuangY,WongamornthamS,KastingJ,etal.Reninincreases[5]AtlasSA.Therenin-angiotensinaldosteronesystem:pathophysio鄄
8、mesangialcelltransforminggrowthfactor-beta1andmatrixpro鄄logicalroleandpharmacologicinhibition.JManagCarePharm,teinsthroughreceptor-mediated,angiotensinII-independent2007,13(8SupplB):9.mec
