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时间:2019-05-31
《轻度认知功能障碍的研究进展》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据国隧耋生医堂盘壶垫!Q生§旦筮21鲞筮2魍!坐』逝坐:§!业垫!Q:y丛:!!盟Q:兰[10][11][123[13][14][15]spinalcordinjuryreducesbrainderivedneurotrophicfactorexpressioninrathippecampns[J].Neuro-science,2009。159:936—939.ZhaoChurunei,DengWei,GageFH.Mechanismsandfunctionalimplicationsofadultneurogenes
2、is[J】.Cell,2008,132(4):645—660.BleschA.TnszynskiMH.Transientgrowthfactorde.1iverysustainsregeneratedax帆8afterspinalcordinju-ry[J].JNeurosci,2007,27(39):10535—10545.LaskeC。StranskyE,LeyheT。eta1.Stage一赫pendentBDNFserumconcentrationsinA]zheimer’edisease[J].JNeuralTran
3、sm。2006,113:1217一1224.PengS,GarzonDJ,MarcheseM,eta1.Decreasedbrain—derivedneurotrophicfactordependsonamyloidaggregationstateintransgenicmousemodesofA]zhei·mer’sdisease[J].JNeurosci。2009,29(29):9231—9239.LeyheT,EschweilerGW,StranskyE,eta1.IncreaseofBDNFserumconcentr
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5、yleyS.Neumtransmitter.pe叩deandcytokineprocessinrelationtodepressivedisorder:comorbiditybetweendepressionandneu静degerativedisorders[J】.ProgNeurebiol,2008,85(I):1—74.FrotunatoJJ,R6啪GZ,KitschTR,eta1.Acutehal"mineadministrationinducesantidepressive—likeeffectsandincrea
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7、onofthebrain—derivedneurotrophicfactorVal66Metpoly-morphismwitlIreducedhippocampalinmajordepres-sion[J].ArchGenPsychiatry。2007。64:410—416.GueriniFR,BeghiE,RiboldazziG。eta1.BDNFVai66MetpolymorphismisassociatedWitlIcognitiveimpairementpatientswitlIParkinson’edisease[
8、J】.EurJNeurol,2009。16(11):1240—1245.轻度认知功能障碍的研究进展毕莉珠何迎春张如富杭州市中医院老年病科,杭州310007中国<2010—02—0l收稿)摘要轻度认知功能障碍是近年的研究热点,是介于正常老化与痴呆之间的过渡状态。本文拟从概念演变、诊断流程、临
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