不同胎龄儿血磷、血钙、碱性磷酸酶及25羟维生素d变化规律研究

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1、授予单位代码10089B癸号或申请号13613HebeiMedicalUniversity硕士学位论文在职科学学位不同胎龄儿血磷、血钙、碱性磷酸酶及25羟维生素D变化规律研究学位申请人：周凤导师：张会丰教授专业：儿科学二级学院：第二医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果,其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文,第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则

2、，承担相应法律责任。研究生签名：i4IR导师签章:级学院领导盖章：⑷年j月0日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外,文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名：导师签章：yf>^/5¥rM今日目录中文摘要·············································································1英文摘要····································

3、·········································3研究论文不同胎龄儿血磷、血钙、碱性磷酸酶及25羟维生素D变化规律研究前言·············································································5材料与方法····································································6结果·································································

4、············7附图·············································································9附表·············································································11讨论·············································································12结论········································

5、·····································14参考文献·······································································15综述早产儿代谢性骨病························································19致谢···················································································31个人简历······················

6、·······················································32中文摘要不同胎龄儿血磷、血钙、碱性磷酸酶及25羟维生素D变化规律研究摘要目的：本研究通过检测不同胎龄新生儿血清磷(P)、钙(Ca)、碱性磷酸酶(ALP)、25羟维生素D（25OHD）的变化规律，为预防早产儿代谢性骨病，早期补充钙、磷提供临床参考。方法：选择2013年10月至2014年2月于石家庄市第四医院出生的新生儿共160例（胎龄27～41周；出生体重850-4050g)，将此160例新生儿进行分组：根据孕周数将新生儿分三组，A组为孕27-34周，共56例，女21例，男35

7、例；B组为孕35-36周，共68例，女24例，男44例；A组和B组为早产儿组；C组为孕37-41周足月儿组，共36例，女19例，男17例。本研究分别对三组不同胎龄新生儿血清磷、钙、ALP、25羟维生素D进行检测比较，应用SPSS统计软件对所提供的样本数据进行分析，研究出不同胎龄新生儿血清磷、钙、ALP及25羟维生素D的变化规律。结果：A组新生儿血磷值为2.34±0.63mmol/L与C组1.98±0.45mmol/L比较，差异有统计