多焦视网膜电图对钝伤性睫状体分离眼手术前后视功能的评价

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1、中国实用眼科杂志2010年5月第28卷第5期ChinJIcl_Opbthalmol,May2010，Vol28，No．5·489·一—·论著：临床研究·多焦视网膜电图对钝伤性睫状体分离眼手术前后视功能的评价。裴文周南【摘要】目的应用多焦视网膜电图研究钝伤性睫状体分离眼手术前后各部位视网膜功能，探讨睫状体分离眼视功能损害机制，为治疗及手术方法的选择与改进，预后的评估提供参考。方法应用VERISscienceTM4．2多焦电生理系统对43例钝伤性睫状体分离眼术前术后及对侧眼进行mfERG检测，以mfERG一阶反应N1波、P1波的振幅密度、潜时为分析指标

2、，对不同视网膜区域包括6个离心度，中心凹、黄斑区、黄斑外区进行检测。对视力与mfERG的关系进行分析。结果钝伤性睫状体分离组患眼手术前后的mfERG比较：N1、P1波振幅密度术后较术前明显提高，术后潜时较术前缩短，在6个环差异均有统计学意义(P0．05)，术前视力与术后mfERG存在等级相关(P

3、<0．05)。结论mfERG能对钝伤性睫状体分离眼视网膜功能进行定位定量测量。【关键词】多焦视网膜电图；钝伤性睫状体分离；视功能AssessmentofvisualfunctionwithMultifocalElectroretinograminpatientswithcyclodialysiscleftbeforeandaftersurgeryPEIWen，zHoUNan，TianjinEyeHospital，Tianjin300040，China【AbstractlObjeetiveInordertogiveaconvenientcriteri

4、ontoselectandimprovetheoperationskillsaswellasprovideausefulreferencetoprognosis，multifocalelectroretinalgram(mfERG)wastakentostudythevariousfunctionoftheretinaindiferentlocationsandthemechanismofthedamagetothevisualfunctionofthecyclodialysiscleftbeforeandaftersurgery．MethodsT

5、hemfERGof43cyclodialysisclefteyesbeforeandaftersurgeryandthefelloweyeswererecordedbyVERISEScienceTM4．2multifocalvisualevokedre—sponseimagingsystem．BasedonthefirstorderkernelofN1andP1waves，changesindifferentareaincludingthediferenteccentricities，centralfoveal，macularareaandextr

6、a．macularareawereinvestigated．ResultsThecomparisonofmfERGofcyclodialysisclefteyesbeforeandaftersurgeryshowedthattheamplitudeofP1andN1wavesincreasedinsixringsaftertheoperation．Thelatenciesalsoshortened．Thedifferencesinsixringswerestatisticallysignificant(P<0．01)．Thecomparisonof

7、mfERGoftheaffectedeyesofcyclodialysisclefteyesaftersurgeryandthefelloweyes，thelatenciesofN1andP1waveinsixringsweresignificantlydelayed(P<0．01)andtheiramplitudesin1-6ringsmarkedlydecreasedinthegroupofcyclodialysisclefteyes(P

8、dorientationaldetectionforthevisualfunctionoftheeyeswiththecy