糖尿病肾病维持性血液透析患者骨密度的测定结果分析

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1、辭倒寺患SS密Igo靈翱析I3~iI三I2018-03-2001:26:12中国现代医生2018年1期王超超林永强赵润英蔡小巧陈琪表1两组患者一般资料比较捋标1)、组(z28)IIi)^l(n=35)p性别(女性)

2、n(%)

3、10(35.71)12(34.29)>0.05年龄(2■岁)56.21±15.6356.54±I5.<>6>(105透析舲(月)

4、M(P25・P75)

5、44(22-60)45(20-62)>0.05BMKx^.kg/m2)22.刃±3,6623.44x3.72>0.05llb(.r±A1

6、01.42±13.76IO2.27±12.14>0.05232.72t85.49294.31x8956>0.052.25±0.242.23±().I9>0.05Pi(x±s,nmH>l7L)L88±0.621$2±O・56>0.05CRP(mg/L)[M(P25.P75)]9.53(3.82550)&53(453-36.52)>0.05KTA'(i±s)L22±O.I2L26±O.2I>0.05表2两组骨质疏松检査悄况组别nTMitW少忖质疏松快榕"'11)(ing/rn?)全BMD(mg/

7、(14.29)7(25.00)17(60.71?0.81±(L23BO.63±O,2(?II：DN组3511(31.43)15(42.86}9(25.71)(h95±O」8().79±O.2I別ffi1.6642」837.8622.7113.271rffi0J970.1400.0050.0090.002［摘要］目的对糖尿病肾病(diabeticnephropathy,DN)维持性血液透析(maintenancehemodialysis,MHD)患者骨质疏松症(osteoporosis,OP)患病情况进行测定分析

8、,探讨DN维持性血液透析患者0P情况。方法选择MHD患者63例，其中DN28例，非DN35例，采用双能X线骨密度仪测定骨密度(bonemineraldensity,BMD),同时收集患者一般资料和血清指标，了解0P的患病情况。用SPSS17.0软件进行统计学分析。结果DN组0P总患病率为60.71%,高于非DN组(25.71%),骨折发生率增高，BMD降低，差异有统计学意义(P<0.05)。结论DN维持性血液透析患者较非DN维持性血液透析患者骨密度更低，0P患病率及骨折发生率更高，应定期检测并给予针对性治疗。［

9、关键词］糖尿病肾病；血液透析；骨质疏松；患病率［中图分类号］R587.2；R692.5［文献标识码］A［文章编1673-9701(2018)01-0008-04AnalysisofthemeasurementresultsofbonemineraldensityinmaintenaneehemodialysispatientswithdiabeticnephropathyWANGChaochaolLINYongqianglZHAORunyinglCAIXiaoqiaolCHENQi21.Departmentof

10、Nephrology,WenzhouTraditionalChineseandWesternMedicineHospitalinZhejiangProvinee,Wenzhou325000,China；2.DepartmentofNephrology,HuzhouFirstPeople'sHospitalinZhejiangProvince»Huzhou313000,China［Abstract］ObjectiveToinvestigatetheprevaleneeofosteoporosis(OP)india

11、beticnephropathy(DN)patientswithmaintenancehemodialysis(MHD)bymeasuringandanalyzingtheprevaleneeofosteoporosis(OP)indiabeticnephropathy(DN)patientswithmaintenancehemodialysis(MHD).Methods63patientswithMHDwereselected,including28casesofDNand35casesofnon-DN.Th

12、ebonemineraldensity(BMD)wasmeasuredbydual-energyX-rayabsorptiometry.ThegeneraldataandserumindexeswerecollectedtounderstandtheprevalenceofOP.StatisticalanalysiswasperformedusingSPSS17.0software.R