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1、酮咯酸氨丁三醇复合酒石酸布托啡诺用于急性骨折术后疼痛的临床疗效观倪绍端1马从学1王光磊2（1江苏泗阳县人民医院223700,2江苏徐州医学院附属医院麻醉科221000）ClinicalobservationofthepostoperativepainofacutefractureaboutketorolacammoniabutylalcoholthreecombinedwithbutorphanoltartrateShao-duanNi1Cong-xueMa1Guang-leiWang2(LSiyangPeople’sHospital，JiangsuProvince,223700,2>Anes
2、thesiologyDepartment，AffiliatedHospitalofXuzhouMedicalCollege,JiangsuProvince,221000)[Abstract]Objective:Toinvestigateclinicaleffectaboutthesingleuseofketorolacammoniabutylalcoholthreeandketorolacammoniabutylalcoholthreecombinedwithbutorphanoltartrateforpostoperativepaintreatmentofacutefractures.Met
3、hods:acutefractureofpostoperativepainaftertreatmentinpatientswith80cases,usingketorolacammoniabutylalcoholthreeorcombinedwithbutorphanoltartratetreatment,wererandomlydividedintotwogroups,40casesineachgroup,Thetwogroupswereintravenousloadingdoseofketorolacammoniabutylalcoholthree30mg,sustainedby2ml/h
4、infusion,respectively,ofintravenousketorolacammoniabutylalcoholthree0.5mg/kg(groupA),ketorolacammoniabutylalcoholthree0.25mg/kg+butorphanoltartratelOmg(groupB)fortreatment,usingvisualanaloguescale(VAS)scoreevaluationbeforeadministration(Tl)，afteradministrationof10min,1h，2h，4h，6h(respectivelyT2,T3,T4
5、,T5,T6)analgesiceffect,andrecordtheadversereaction.Results:(1)withingroupcomparison:comparedwithTl,twogroupsofT2,T3,T4,T5,T6,VASscoredecreasedsignificantly,thedifferencewasstatisticallysignificant(P<0>05);therewasnodifferenceinVASscoresinT2,T3,T4,T5(P>0.05);VASscoreincreasedinT6,thedifferencewasstat
6、isticallysignificant(P<0.05).(2)betweenthetwogroups:Tl,T2,T3,T4,T5VASscoresofthetwogroupshadnosignificantdifference(P>0.05);T6AVASscoreingroupislowerthanBgroup,thedifferencewasstatisticallysignificant(P<0.05);Breducedthestomachdiscomfort,retchingorvomitingadversereactionwasAgroup,thedifferencewassta
7、tisticallysignificant(P〈0.05))•Conclusion:acutefractureofpostoperativepainafterusingketorolactromethamine,Dingthreeketoneorketorolacammoniabutylalcoholthreecombinedwithbutorphanoltartrateforanalgesiae
