妇科肿瘤手术患者泌尿系感染病原菌分布及相关因素分析

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1、妇科肿瘤手术患者泌尿系感染病原菌分布及相关因素分析郑芝李小萍淮丽金小青赵宇胡越王丽芳姚招温州医科大学附属第二医院妇科病区摘要：目的探讨和分析妇科肿瘤手术患者泌尿系感染的相关因素及病原菌分布情况。方法选取2014年1月-2016年12月期间于医院进行妇科肿瘤手术的150例患者为研宄对象，并分别对妇科肿瘤手术患者的年龄、手术方式、手术持续吋间、合并糖尿病、应用抗菌药物、留置导尿管、住院时间等相关因素以及病原菌分布和耐药等情况予以全而深入的统计和分析。结果150例妇科肿瘤手术患者中发生泌尿系感染28例，感染率为18.67%;28例妇科肿瘤手术泌尿系感染患者中共检出病原菌34株

2、，以革兰阴性菌为主，共24株占70.59%;Logistic回归分析结果显示，手术方式、应用抗菌药物及留置导尿管是妇科肿瘤手术患者泌尿系感染的独立危险因素（P〈0.05）;主要革兰阴性菌对头孢哌酮、头孢噻肟、哌拉西林均表现出较高的耐药性，耐药率均＞50%。结论应注意引起妇科肿瘤手术患者泌尿系感染的发生的独立危险因素，病原菌主耍以革兰阴性菌分布为主，临床上应根据具体耐药情况科学使用抗菌药物。关键词：馳肿瘤;泌尿系感染;危险因素;病原菌分布;收稿日期：2017-07-11Distributionofpathogensandriskfactorsinurinarytracti

3、nfectionsofthepatientswithgynecologicaltumorsurgeryZHENGZhiLIXiao-pingHUAILiTINXiao-qingZHAOYuHUYueWANGLi-fangYAOZhao-nanTheSecondAffiliatedHospitalofWenzhouMedicalUniversity;Abstract：OBJECTIVEToprobeintoriskfactorsanddistributionofpathogensinurinarytractinfectionsofthepatientswithgyneco

4、logicaltumorsurgery.METHODSAtotalof150patientswithgynecologicaltumorsurgeryinthehospitalfromJan.2014toDec.2016wereselectedastheclinicalstudyobjects.Therelatedfactors,includingage,surgicalmethods,durationofoperation,diabetesmcllitus,applicationofantibiotics,indwellingcatheters,hospitaliza

5、tiontime,aswellasthedistributionofpathogensanddrugresistance，werecountedandanalyzedindetail.RESULTSTherewere28caseswithurinarytractinfectionsin150patientswithgynecologicaltumorsurgery,andtheinfectionratewas18.67%.Totally34strainsofpathogensweredetectedfrom28casesofgynecologicaltumorsurge

6、rypatientswithurinarytractinfections,whichweremainly24strainsofgram-negativebacteria,accountingfor70.59%.Logisticregressionanalysisshowedthatthesurgicalmodes,applicationofantibioticsandtheindwellingcatheterwereindependentriskfactorsofurinarytractinfectionsingynecologicaltumorsurgerypatie

7、nts(!)<()•05)•Themaingram-negativebacteriahadhighresistancetocefoperazone,cefotaximeandpiperacillin,andtheresistantrateswereallmorethan50%.CONCLUSIONAttentionshouldbepaidtotheindependentriskfactorsforurinarytractinfectionsingynecologicaltumorsurgerypatients.Thedistributio