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1、29AutismSpectrumDisorderandPervasiveDevelopmentalDisordersinChildrenByStephenCowan,MD,FAAPfrom“IntegrativeMedicineforChildren”editedbyDr.MayLoo,2008SaundersTerminology1.ClinicalConsiderationinAutism2.Etiology:a.GeneticInfluencesb.PrenatalInfluencesc.Post-natalInfl
2、uencesd.GastrointestinalInflammationinautism3.ConventionaldiagnosisofAutism4.DifferentialDiagnosis5.ConventionalmanagementofAutism6.CAMmanagementconsiderations:a.The"leakygut"syndromeandautismb.TreatingDysbiosisc.HealingtheGutd.StrengtheningImmunityandDetoxificati
3、one.ChelationofToxicElementsf.Neuro-metabolicFine-Tuning7.HolisticManagementConsiderations(author'sexperience)8.Summary9.References29AutismSpectrumDisorderandPervasiveDevelopmentalDisordersinChildrenByStephenCowan,MD,FAAPOverthepast10yearstherehasbeenasignificantr
4、iseinthediagnosisofAutismSpectrumdisorder(ASD)inNorthAmericaandEurope.Whatwaspreviouslyfelttobeararegeneticdisorderwithaprevalenceof1:2000nowisestimatedtobeashighas1:165children.BertrandJ,etal:PrevalenceofautisminaUnitedStatespopulation:theBrickTownship,NewJerseyi
5、nvestigation.Pediatrcis108:1155-1161,2001,NewschafferCJ,etal:NationalautismprevalencetrendsfromUnitedStatesspecialeducationdata.Pediatrcis115:e277-e282,2005Initialdenialbythemedicalcommunityofasignificantriseinprevalencehasbeenrefutedbystudiesthathaveshownthisnott
6、obeduetoimproveddiagnosticsorshiftsinthecriteriafordiagnosis.Byrd,RS,ReporttotheLegislatureonthePrincipalFindingsfromtheEpidemiologyofAutisminCalifornia:AComprehensivePilotStudy.SanDiego:MINDInstitute,UniversityofCalifornia,Davis;2002.TheEpidemiologyofAutisminCali
7、fornia:AComprehensivePilotStudyYeargin-AllsoppM,etal:PrevalenceofautisminaUSmetropolitanareas.JAMA289:49-55,2003Theacknowledgementthatgeneticsyndromesdonotriseepidemicallyhasledresearcherstosearchforpossiblealternativeexplanationsforthisdevastatingsyndrome.Termino
8、logyTheterm"Autism"wasoriginallycoinedbyLeoKannerin1943andfurtherdescribedbyHansAspergerin1944.Theydescribedasomewhatheterogeneousgroupofchildrenwithanu
