梅毒感染孕妇发生围产儿死亡的临床分析及防治措施

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1、梅毒感染孕妇发生围产儿死亡的临床分析及防治措施［］目的：研究20例感染梅毒的孕妇发生围产儿死亡的临床特点及探讨防治措施。方法：对2009年01月至2015年06月在东南大学附属第二医院收治的发生围产儿死亡的20例梅毒孕妇的临床资料进行回顾性分析。结果：发生围产儿死亡的梅毒孕产妇20例，12例（60%）孕产妇孕期未建卡，8例建卡中仅5例（20%）正常产检，且均行驱梅治疗。20例孕妇中16例（80%）无业，仅2例为大专以上学历。分娩前梅毒血清学高滴度（RPR≥l:8）的孕妇有15例，其中11例（73.3%）死婴为梅毒儿。低滴度（＜1:8）的孕妇

2、有5例，仅有1例（20%）为梅毒儿。20例中有14例为死胎，其中有9例（64.3%）考虑胎传梅毒；6例新生儿死亡中3例（33.3%）具有梅毒儿的特征。结论：应加强人群健康教育和孕前孕期梅毒血清筛检管理，及时行驱梅治疗，努力将梅毒对妊娠的危害降至最低限度。［关键词］妊娠期梅毒围产儿死亡预防方法D0l:10.3760/cma.j.issn.0376-2491.2016.36.37作者单位：210003，江苏省南京市，东南大学附属第二医院妇产科通信作者：岳欣，Email：yuexintiantian@sohu.com。Theinvestigationo

3、fperinataldeathinpregnantwomenwithsyphilisanditspreventionmeasures（Aclinicalanalysisof20cases）WangYan,YueXin,DingYi,tangjuan，LiQianrui,Abstract：ObjectiveToinvestigatetheclinicalfeatures,preventivemeasuresofperinatalfetaldeathin20caseofpregnantwomenwithsyphilis.MethodsAlltheda

4、teofpregnantwomeninfectedwithsyphilisfromJanuary2009andJune2015inSecondAffiliatedHospitaloftheSoutheastUniversitywerecollectedandclinicalcharacteristicsof20casesofsyphilisinpregnantwomenwereanalyzedretrospectively.Results20casespregnantwomeninfectedwithsyphilisemergedperinata

5、lfetaldeath,12cases(60%)inpregnantwomenwasnotbuildingperinatalcards,only5casesof8buildingcards(20%)wasregularproductioninspection,andreceivedantisyphilitictreatment.16cases(80%)of20casespregnantwomenwasunemployed,only2casesweregraduatedfromjuniorcollegeorabove.Thereare15cases

6、ofpregnantwomenwithsyphilisserologyhightitersbeforedelivery(RPR≥l:8),ofwhich11cases(73.3%)childrendeadforsyphilis.Thereare5casesofpregnantwomenwithsyphilisserologylowtitersbeforedelivery(<l:8),ofwhichonly1case(20%)childrendeadforsyphilis.14casesisstillbirth,includingnin

7、ecases(64.3%)considercongenitalsyphilis;3casesof6casesofneonataldeaths(33.3%)hadsyphilischildcharacteristics.ConclusionWeshouldstrengthenhealtheducationandscreeningforsyphilismanagementbeforeandduringpregnancy,timelyantisyphilitictreatmentappearstoreducetheharmofsyphilis.Keyw

8、ords：Pregnancywithsyphilis；Perinatalfetaldeath；Preventionmethod梅毒(sy