最新病理学经典图片集课件ppt.ppt

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1、病理学经典图片集前言共和国二十一世纪第五个生日即将到来的时刻，精心制作了这个图片集，其中涉及了大量精美的、高质量的图片，并附带了大量而且详尽的文字说明。值六一儿童节即将到来之际，把它献给祖国，也献给奋战在医疗一线的战友。2005.05.21EsophagealVarices第一部分Showsthrombosisofalargesubmucosalvarix.Notetheulcerationoftheoverlyingmucosa(arrow)andinflammationofthesubmucosalstroma.SquamousCellCarcinomaoftheEsophagus

2、第二部分Gross:Thisisanexampleofanulceratedsquamouscellcarcinomaoftheesophagus.Itdiffersfromabenignpepticulceroftheesophagusinthatitisamuchlargerlesionandratherthanbeingsharplypunched-out,ithasirregularborders.Notetheperforationinthecenter.Isalowpowerviewofthehistologicsectioninyourclassset.(M=mucosa

3、;Sm=submucosa;Mp=muscularispropria).Theintactmucosaistotheleftofthearrow;theulceratedcarcinoma(C)istotheright.Istakenatthejuncture(arrowhead)ofthenormalmucosa(M)andtheulceratedcarcinoma(C)anditshowsanothercommonfeatureofesophagealcancer.Thegrossmarginsofthecancerareoftenmisleadingbecausethetumor

4、frequentlyspreadslongitudinallyinsubmucosallymphatics(doublearrows).Isasectiontakenthroughthefullthicknessoftheesophagealwall.Carcinomasoftheesophagusaretypicallydeeplyinfiltratinglesionsandthisonehasextendedthroughthemuscularispropria(arrows).Showsnestsofmalignantsquamouscellswithinthesubmucosa

5、.Thisisamoderatelydifferentiatedsquamouscellcarcinomainthatthereiskeratinproduction.Themalignantcellsshowacommonfeatureofmalignancy,namelyalteredpolarity.Thedifferentiatingsquamouscellswithinthesubmucosalnestscannotsloughkeratintotheluminalsurface.Insteadthekeratinaccumulatesinthecenterofthenest

6、sassphericalkeratin"pearls"(arrow).Showsthemoderatelydifferentiatedsquamouscellcarcinomawithkeratinpearlsathigherpower.Mitoticfiguresareusuallycommoninmalignanttumorsandoftentheyareabnormal.Thisisatripolarmitosisandifyoulookcarefullyyoucansee3mitoticspindles.ChronicPepticUlceroftheStomach第三部分Gro

7、ss:Chronicpepticulcersaretypicallysmall(lessthan4cmindiameter),round,sharplypunched-outlesionswithperpendicularwallsandacleanbase.Fibrouscontractureofthebaseoftheulcermaycausepuckeringofthesurroundingmucosalfoldssuchthatthey