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ID:6213817
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时间:2018-01-06
《精氨酸牙膏对釉质早期龋再矿化作用探究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、精氨酸牙膏对釉质早期龋再矿化作用探究 [摘要]目的研究精氨酸牙膏对人牙釉质早期龋的再矿化效果。方法制备人牙釉质龋标本,随机分为3组:空白组(去离子水处理),对照组(普通市售含氟牙膏处理,含质量分数0.14%单氟磷酸钠),实验组(精氨酸牙膏处理,含质量分数0.14%单氟磷酸钠和8%精氨酸)。经体外pH循环10d,测量pH循环前后各组样本的表面显微硬度,计算其差值;并通过偏光显微镜观察各组样本再矿化前后的形态学改变。pH循环结束后,脱矿处理2h,测量其表面显微硬度,计算与pH循环前的差值,评估再矿化处理对釉质抗酸能力的影响。采用酸蚀法测定各组的
2、氟摄入量。结果与对照组和空白组比较,实验组釉质表面的显微硬度、抗酸能力,以及氟摄入量均明显升高。偏光显微镜下观察,实验组病损深度明显变浅,且有表层下再矿化条带,而空白组与对照组病损无明显变化。结论精氨酸牙膏能有效促进人牙釉质龋表层及表层下再矿化,在早期龋的防治领域具有较大的临床应用前景。[关键词]釉质早期龋;精氨酸牙膏;精氨酸;再矿化[中图分类号]R781.1[文献标志码]A[doi]10.7518/hxkq.2014.01.00810Effectofargininedentifriceonremineralizationofinitiale
3、namelcariouslesionsXuPengcheng,DengMeng,ZhouXue-dong,LiJiyao,ChengLei,XuXin.(StateKeyLaboratoryofOralDiseases,Dept.ofConservativeDentistryandEndodon-tics,WestChinaHospitalofStomatology,SichuanUniversity,Chengdu610041,China)[Abstract]ObjectiveToevaluateremineralizationeffica
4、cyofanargininecontainingdentifriceoninitialenamelcariouslesionsinvitro.MethodsHumanenamelblockswithearlylesionswerepreparedandrandomlydividedintothreetreatmentgroups:negativecontrolgroup(distilledanddeionizedwater),positivecontrolgroup(fluoridecontainingdentifriceand0.14%so
5、diummonofluorophosphate),andtestdentifricegroup(8.0%arginineand0.14%sodiummonofluorophosphate).ThelesionsweresubjectedtoapH-cyclingregimefor10days.SurfaceenamelmicrohardnessoftheenamelblocksfromeachgroupwasmeasuredbeforeandafterpHcycling,andthesurfacemicrohardnessrecoverywa
6、scalculated.Then,10specimenswereanalyzedforenamelfluorideuptake(EFU)throughacidetchingmethod,afterwhichtheyweretreatedindemineralizationsolutionfora2hperiodofacidchallenge.Theotherspecimensweresectionedandexaminedthroughpolarizedlightmicroscopy.ResultsInthetestdentifricegro
7、up,microhardnessrecoveryandEFUweresignificantlyhigherthanthoseinthenegativecontrolandpositivegroups.Thetestdentifricegroupwassignificantlyresistanttotheacidchallengecomparedwiththeothergroups.Conspicuousremineralizationofenamelsubsurfacelesionswasobservedunderpolarizedlight
8、microscopyamongsamplestreatedwithtestdentifrice,whereasthecontrolgroupsshowednosig
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