最新A systematic review of the prevalence of schizophrenia：精神分裂症的患病率的系统评价PPT课件.ppt

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1、Asystematicreviewoftheprevalenceofschizophrenia：精神分裂症的患病率的系统评价Schizophrenia-themostcommonformofpsychosis–ischaracterisedbydisordersofcognition(egparanoia),affect(mood),communication(thoughtdisorder)andperception(eghallucinations)–leadingtoalossofcontactwithrealityalongwithvariousformsofimpair

2、edbehavior.[old]Becauseschizophrenia(a)hasanearlyonsetand(b)hasarelapsingorchroniccourse,itisasignificantpublichealthproblem.Itranksinthetop10leadingcausesofdisability,withaburdenofdiseasecomparabletocancerandgreaterthanheartdisease.[old]Understandingtheprevalenceofschizophreniahasimportantim

3、plicationsforbothhealthserviceplanningandriskfactorepidemiology.[new]AimsTosystematicallyidentifyandcollatestudiesoftheprevalenceofschizophreniaTosummarizevariationintime,placeandpersonbyexaminingthedistributionoftheseestimatesofprevalenceToexplorefactorswhichmayinfluenceprevalenceestimatesMe

4、thods:systematicreviewElectronicdatasearchMedline,PsychoInfo,Embase,LILAC1965-2001inclusive(schizo*ORpsycho*)ANDincidenceORprevalence)alsoReviewarticlebibliographyWrotetoauthorsScreenabstractandreviewedpaperstocullirrelevantcitationsRateitemsanddiscretedataNon-overlappingSexMale,FemaleOverlap

5、pingAgeegallagesorage15-54DiagnosisegCategoS+orCategoSPO+clinicalDiagnosticcategoriesegDSMIVSchizophreniaorSchizophrenia+DelusionaldisorderSiteoverlapegDenmarkorCopenhagenEpochoverlapeg1990-92or1989-91Dataanalysis:examplecumulativedistributionRateper100,000ResultsElectronicsearch=834potentia

6、lpapersManualchecking=249potentialpapersLettersfrom52authors,whoprovidedanadditional41referencesOfpotentiallyrelevantpapers,74%wereidentifiedfromelectronicsourcesResults(2)Ratesbasedon176,056potentiallyoverlappingincidentcasesAfterreview158wereincludedfrom32countriesTypesofstudiesCorestudies=

7、100Migrantstudies=24Cohortstudies=23Otherspecialgroups=14CorePrevalenceStudiesSexdifferencesMale:femalerateratioMigrantstatusUrban-ruraldifferencesCohortstudiesAustralia(n=2)Denmark(n=3)Finland(n=5)Israel(n=2)Italy(n=1)Sweden(n=2)TheNetherlan