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ID:6060614
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时间:2018-01-01
《乳腺癌胸腔镜内乳淋巴结清扫术临床探究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、乳腺癌胸腔镜内乳淋巴结清扫术临床探究 [摘要]目的探讨胸腔镜下行内乳淋巴结清扫术治疗乳腺癌的临床效果。方法选择本院2008年5月~2012年9月收治的乳腺癌内乳淋巴结转移高风险患者24例,其中14例患者在乳腺癌改良根治术后采用胸腔镜下内乳淋巴结清扫(观察组),10例行乳腺癌改良扩大根治术(对照组),比较两组患者的术中出血量、检出淋巴结数、转移和生存率、并发症等。结果观察组出血量明显低于对照组(P0.05)。结论乳腺癌胸腔镜内乳淋巴结清扫术相比乳腺癌改良扩大根治术更简便、安全、微创,且可为乳腺癌分期、治疗计划制订、
2、预后评估提供更全面的信息。[关键词]乳腺癌;胸腔镜;内乳淋巴结清扫术[中图分类号]R737.9[文献标识码]A[文章编号]1674-4721(2013)11(a)-0027-03ClinicalresearchonthoracoscopicinternalmammarylymphnodesdissectionforbreastcancerHEChunXUChen-yangHUANGXing-weiHUANGMou-qingYUANHuo-zhongZHANGGong-liangXIAOZhen-yuXIXunThe
3、SecondDepartmentofGeneralSurgery,People′sHospitalofGanzhouCityinJiangxiProvince,Ganzhou9341000,China[Abstract]ObjectiveToexploretheclinicaltherapeuticeffectsofthoracoscopicinternalmammarylymphnodesdissectioninthetreatmentofbreastcancer.Methods24breastcancerpat
4、ientswithhighriskofinternalmammarylymphaticmetastasisadmittedintoourhospitalfromMay2008toSeptember2012wereselected.Amongthem,therewere14patientswereappliedwiththoracoscopicinternalmammarylymphnodesdissectionaftermodifiedradicalmastectomyforbreastcancer,whichwe
5、reclassifiedintoobservationgroup.Therest10patientswereonlyperformedwithmodifiedextendedradicalmastectomyforbreastcancer,andselectedascontrolgroup.Theintraoperativebloodloss,theamountofdetectedlymphnodes,ratesofmetastasisandsurvival,andcomplicationswerecompared
6、inbothgroups.ResultsTheintraoperativebloodlossintheobservationgroupwasremarkablylowerthanthatofthecontrolgroup(P0.05).ConclusionIncomparisonwithmodifiedextendedradicalmastectomyforbreastcancer,thethoracoscopic9internalmammarylymphnodesdissectionismicro-invasiv
7、e,easierandsafer.Besides,itprovidesthemorecomprehensiveinformationforstagingofbreastcancer,formationoftherapeuticscheme,andevaluationofprognosis.[Keywords]Breastcancer;Thoracoscope;Internalmammarylymphnodesdissection乳腺癌淋巴结转移是临床上进行分期和评估预后的有效指标,正常人乳房有3/4淋巴液引流到腋窝
8、淋巴结,而只有内侧1/4淋巴液引流至内乳淋巴结,由于以往的研究显示,内乳淋巴结清扫相对于传统Halsted根治术并不能显著提高生存率,因此对内乳淋巴结的处理一直未受重视[1-2]。内乳淋巴结链沿胸廓内的动静脉走行,淋巴结数目为3~7枚,多处于1~3肋间隙前端结缔组织和脂肪内,双侧的内乳淋巴结链于胸骨后与淋巴管穿支相连接,属于肿瘤向对侧进行扩散的主要途径之一[
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