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1、AnIntroductionToTheHealthEffectsofMetals金属的健康影响导论Chromium(Cr)Copper(Cu)Iron(Fe)Magnesium(Mg)Manganese(Mn)Selenium(Se)Zinc(Zn)NutritionallyImportantSomemetalshaveveryimportantphysiologicalfunctionsCrCuFeMgMnSeZnUse–essentialelement,associatedwithinsulin,stainlesssteel,tanningleatherSource–
2、foodsupply,inhalationRecommendeddaily–50-200µgAbsorption–intestineToxicity–acuteexposurecausekidneydamage,lungcancerandlivercancerFacts–comesindifferentoxidizedforms–Cr3+,Cr6+ThetoxicityofCr6+is100foldofCr3+使用–基本元素，与胰岛素、不锈钢、鞣皮源–food供应、吸入推荐每日–50-200µ吸收–肠毒性–急性暴露造成肾脏损害、肺癌和肝癌事实关联–有不同氧化形式–Cr3+
3、Cr6+Cr6+的毒性是的Cr3+100倍Chromium(Cr)Use–oxygencarryinghemoglobin(血色素）Source–foodRecommendeddaily–10-15mgAbsorption–intestineToxicity–excesscausesbloodyfesses,bloodyvomit,liverdamageFacts-3-5gramsinthebody67%associatedwithhemoglobinIron(Fe)Use–essentialnutrient,associatedwithmanyenzymes,antac
4、idsRecommendeddaily–280-350mgSource–foodsupply,nuts,cereals,seafood,meats,drinkingwaterAbsorption–smallintestineToxicity–deficiency–convulsions（痉挛）-excess–nervoussystemFacts–20gramsinbodyMagnesium(Mg)Use–traceelement,associatedwithmanyenzymesSource–foodsupply,grains,nutsRecommendeddaily–2
5、to5mgAbsorption–intestinepoor(5%)Toxicity–inhalation–respiratorydisease,nervoussystem,Parkinson’s-likesyndrome,psychiatricdisordersFacts–half-live37daysManganese(Mn)Use–essentialelement,presentinmosttissue,anticancer,reducestoxicityofmetalmercuryandcadmiumSource–foodsupply,shrimp,meatReco
6、mmendeddaily–55-70µg/day,nottoexceed200µg/dayAbsorption–intestineToxicity–deficiency–heartdisorders-excess–“blindstaggers（晕倒症）”,neurologicaleffectsSelenium(Se)Use–essentialelement,cofactorwithseveralenzymes,andproteinsSource–foodsupply,drinkingwaterRecommendeddaily–12-25mgAbsorption–intes
7、tineToxicity–deficiency–impairedgrowth,neurologicaldisorders,-inhalationcancausemetalfumefeverZinc(Zn)（金属烟雾病）Aluminum(Al)Arsenic(As)Cadmium(Cd)Cobalt(Co)Lead(Pb)Mercury–Inorganic(Hg)Mercury–Organic(Hg-CH3)Nickel(Ni)Tin(Sn)ToxicMetalsPbCoAlAsCdHgHg-CH3NiSnUse–wideran
