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1、生长抑素治疗急性胰腺炎的临床效果分析【摘要】目的：分析生长抑索治疗急性胰腺炎的临床疗效。方法：选择急性胰腺炎患者88例，随机分为治疗组和对照组各44例，对照组给予禁食、胃肠减压、调整水、电解质及酸碱平衡、常规使用抗生素、补充有效血容量、保持肠外营养等对症支持治疗。同时应用低分子右旋糖酹、复方丹参、质子泵抑制剂筹静脉滴注。治疗组在此基础上加用生长抑素3mg加入5%葡萄糖注射液静脉滴注。比较两组腹痛及腹部深压痛消失时间及临床治愈率、治愈时间及死亡率。结果：对照组腹痛及腹部深压痛消失时间(88.3±3.6)h和(170.6±39.1)h与
2、治疗组(49.1±12.1)h、(102.1±38.3)h比较差异有统计学意义(P〈0.05)。对照组治愈率81.82%(36/44),治愈时间(23.6±4.9)d,死亡率18.18%(8/44)。治疗组治愈率97.73%(43/44),治愈时间(16・3土5・5)d,死亡率2.27%(1/44)。治疗组临床治愈率、治愈时间及死亡率与对照组比较差异有统计学意义(1X0.05)。结论：生长抑素对急性胰腺炎的治疗效果显著，可在一定程度上控制病情的发展。【关键词】生长抑索；急性胰腺炎；临床疗效AnalysisoftheClinicalE
3、ffectivenessofSomatostatinintheTreatmentofAcutePancreatitis/WANGWei.//MedicalInnovationofChina,2014,11(32)：128-130[Abstract]Objective：Toanalyzetheclinicalefficacyofsomatostatininacutepancreatitis.Method：88patientswithacutepancreatitiswererandomlydividedintotreatmentgro
4、upandcontrolgroup,controlgroup(44cases)wasgivenfasting,gastrointestinaldecompression,maintainingwater,electrolyteandacid-basebalance,theroutineuseofantibiotics,addingbloodvolume,maintainingparenteralnutritionandothersymptomaticsupportivetreatment・Atthesametimelowmolecu
5、larweightdextran,Danshen,protonpumpinhibitors,suchasintravenousinfusionwereapplied.Treatmentgroup(44cases)wastreatedwithsomatostatin3mgin5%glucoseintravenousinjectioninaddition.Theabdominalpainandabdominaltendernessdisappeareddeeptimeandtheclinicalcurerate,curetimeandm
6、ortalitywerecompared.Result：Inthecontrolgroup,abdominalpainandabdominaltendernessdisappearedtime(88.3±3.6)hand(170.6±39.1)hcomparingwiththetreatmentgroup(49.1±12.1)h,(102.1±38.3)hwerewithstatisticalsignificanl(P<0.05)・Cureratewas81.82%(36/44)inthecontrolgroup,curetimew
7、as(23.6土4.9)d,mortalitywas18.18%(8/44)・Inthetreatmentgroup：thecureratewas97.73%(43/44),curetimewas(16.3+5.5)d,themortaiityratewas2.27%(1/44).Differencesbetweenthetwogroupshadstatisticalsignificance(P<0.05)•Conclusion:Thetherapeuticeffectofsomatostatinonacutepancreatiti
8、sissignificant，itcancontrolthediseaseprogressesinsomeextent.[Keywords]Somatostatin；Acutepancreatitis；Clinicalefficacy
