星形细胞瘤课件.ppt

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1、Lecturer:GuoXiangClassificationandDiagnosisofastrocytoma(星形细胞瘤)MorbidityofAstrocytomaAstrocytictumor78%GliomaPrimarybraintumor40%5-10100000MorbidityTypeofAstrocytomaWHOclassificationⅠ~ⅣⅠ级毛细胞型星形细胞瘤、室管膜下巨细胞星形细胞瘤Ⅱ级弥漫型星形细胞瘤Ⅲ级间变型星形细胞瘤Ⅳ级胶质母细胞瘤PilocyticastrocytomaANDSubependy

2、malgiantcellastrocytomasDiffuseastrocytomaAnaplasticastrocytomaGlioblastomaSubependymalgiantcellastrocytomas-GradeⅠReddish-yellowpimpleschromosomaldisorder染色体疾病epiloia（结节性硬化）8Y~18Y(male-to-femaleratio=3:1)subependymalnodulescontrast-enhancehydrocephalus脑积水favorableclin

3、icaloutcome红黄色丘疹T1T2T1-enhanceCTnon-contrastM16yPilocyticastrocytoma-GradeⅠChildrenCerebellumhemispheresorvermisSolidandcysticpartNormaltissue>solidnodule>cysticmass>CSFindensityonNCCTMRI:ahigh-signal-intensitycystsurroundingaiso-intensitymuralnoduleonT2Contrastenhance

4、mentwithbothCTandMRIvermisF62YT1T2T1-enhancePathology弥漫型星形细胞瘤属于交界性肿瘤，容易复发，且恶性度有不断增加的趋势，最终发展为胶质母细胞瘤。Grade-ⅡDiffuseastrocytomaGrade-ⅢAnaplasticastrocytomaGrade-ⅣGlioblastomaDiffuseastrocytoma-GradeⅡborderlinetumorsurgerymalignancywillbehigherrecurCharacteristicImagingCha

5、racteristicBrainstemorsupratentorialwhitematterpoorlydefinedborderLow-densityonCTslightly>CSFNosignificantenhancementNoorslightlyenhancementCysticchangeT1WIhypointensitysignalT2WIhyperintensitysignalF54YSurgicalfieldandSpecimenThetumorshoweddiffuselyinfiltratedgrowing.

6、NOhemorrhageandnecrosis.Anaplasticastrocytoma-GradeⅢthetumorenhanceddistinctlyT1-enhanceFLAIRT1T2T1Glioblastoma-Grade-ⅣAdulthoodMixeddensityorsignallesionHemorrhageandnecrosisContrast-enhanceBecausethetreatmentofastrocytomaismainlybasedonpathologicaltype,soitwillbevery

7、helpfultomakeanaccuratediagnosistothelevelofcells.ThankYou!ThankYouforYourAttention