欢迎来到天天文库
浏览记录
ID:56484477
大小:248.40 KB
页数:4页
时间:2020-06-24
《涎腺粘液表皮样癌临床病理分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、河南医学研究2Ol3年6月第22卷第3期HENANMEDICALRESEARCHJun2013,Vo1.22,No.3·32l··临床研究·88例涎腺粘液表皮样癌临床病理分析史璐,陈新明(I.郑州大学第四附属医院牙体牙髓科河南郑州450000;2.武汉大学1:3腔医学院病理科湖北武汉430079)摘要:目的:采用Auclair量化分级系统对88例涎腺粘液表皮样癌进行l临床病理分析,探讨组织学分级与肿瘤生物学行为间的关系。方法:根据本次实验的纳入排除标准选择涎腺粘液表皮样癌88例。采用Au—clair量化分级系统对本组病例行组织学分级,并行统计学分析。结果:低
2、度恶性34例(38.6%),中度恶性(Ⅱ级)20例(22.7%),高度恶性(Ⅲ级)34例(38.6%)。Ⅲ级患者年龄长于I级患者,[(43.7±17)s(33.9±13.9)],P<0.05。I级患者l临床症状发生率(21%)低于Ⅱ级(50%)和Ⅲ级患者(76%)(P<0.5)。Ⅲ级病例的肿瘤直径[(3.8±1.4)cm]大于I级[(2.9±1.8)cln]和Ⅱ级病例[(3.5±2.9)cm](P<0.05)。生存分析结果表明性别、临床分期、组织学分级与肿瘤复发显著相关(P<0.05)。结论:应用Auclair量化分级系统对涎腺粘液表皮样癌行组织学分级有助于
3、判断肿瘤的预后。关键词:涎腺;粘液表皮样癌;病理分级;预后中图分类号:R739.8doi:10.3969/j.issn.1004-437X20l3.03.001Aclinic0path0l0gicstudyof88casesofmucoepidermoidcarci-nomaofsalivaryglandsSHILu,CHENXin—ruing(,.DepartmentofEndodontics,TheFourthAffiliatedHospitalofZhengzhouUniversity,Zhengzhou450000,China;2.Departmen
4、tofOralPathology,SchoolofStomatologyofWuhanUniversity,Wuhan430079,China)Abstract:Objective:ToevaluatetheprognosticimportanceofAuclair’Squantitativegradingsys—ternofmucoepiderm0idcarcinoma(MEC)ofsalivarygland.Methods:Eighty—eightMECofsali—varyglandswereclinicopatho1ogica1lyreviewed.
5、Auclair’Squantitativegradingsystemwasused.Clinicalandpathologicfeatureswerestatisticallyanalyzed.Results:Thirty—fourcases(38.6%)wereclassifiedaslowgrade,20(22.7%)asintermediategradeand34(38.6%)ashigh—gradetumors.Patientswithhighgradetumorswereolderonaveragethanthosewithlowgradetumo
6、rs[(43.7±17)5(33.9±13.9)],P<0.05.Theincidenceofclinicalsymptomoflowgradetumors(21%)waslowerthanthatofintermediate(50%)andhighgradetumors(76%)(P<0.05).Tumorsizesofhighgradetumors(3.8±1.4)emwerelargerthanthoseoflow(2.9±1.8)emandintermediategradetumors(3.5±2.9)em(P<0.05).Survivalanaly
7、sisrevealedthatgender,clinicalstageandpathologicgradewerethemajorrecurrenceriskfactors(P<0.05).Conclusion:InMECofsalivaryglands,tumorgrade,subdividingeasesintolow,interme—diateandhighgradebyusingthecriteriadelineatedbyAuclair,correlateswellwithprognosis.Keywords:mucoepiderm0idcarci
8、noma;salivarygland;patholo
此文档下载收益归作者所有