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时间:2020-06-04
《雄激素性秃发的皮肤镜特点及其与临床的关系.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、6422014年9月第47卷第9期Chinr2014.Vo1.47.No.9·论著·雄激素性秃发的皮肤镜特点及其与临床的关系胡瑞铭徐峰盛友渔齐思思韩毓梅缪盈芮文龙杨勤萍【摘要】目的探讨雄激素性秃发(AGA)的皮肤镜特点及其与临床的相关性。方法用皮肤镜观察比较200例男性AGA(MAGA)患者和80例女性AGA(FAGA)患者以及50例健康对照者的头皮区域皮损特点,并收集相关临床资料。结果毛发直径差异>20.O%,见于所有MAGA和88.8%FAGA患者的脱发区域;褐色毛周征可见于47.0%MAGA和41.3%FAGA患者;白色毛周征可见于23.5%MAGA和17.5%FAGA患者;黄点征
2、见于22.5%MAGA和31.3%FAGA患者及14.O%对照者;白点征见于24.O%MAGA和23.8%FAGA患者及18%对照者;局部毛干缺失见于28.5%MAGA、67.5%FAGA患者及2%对照者;头皮色素沉着见于35.0%MAGA和38.8%FAGA患者;鳞屑见于49.0%MAGA和56.3%FAGA患者及50.O%对照者。FAGA患者的毛发直径差异>20%的阳性率低于MAGA患者(P<0.01),而局部毛干缺失的阳性率则高于MAGA患者(P<0.O1)。毛发直径差异>20%见于所有晚期FAGA患者(P<0.05),而褐色毛周征多见于早期MAGA患者(P<0.05),白色毛周征
3、、头皮色素沉着、局部毛干缺失则与AGA的疾病严重程度呈正相关(P<0.05)。结论毛发直径差异、褐色毛周征、白色毛周征、黄点征、白点征、局部毛干缺失、头皮色素沉着及鳞屑均为AGA患者皮肤镜下的常见征象,其中毛发直径差异>20%、褐色毛周征、局部毛干缺失具有特征性。【关键词】秃发;雄激素;皮肤镜检查DermoseopiefeaturesofandrogeneficalopeciaandtheirclinicalimplicationsHuRuiming,XuFeng,ShengYouyu,QiSisi,HanYumel,MiaoYing,RuiWenlong,YangQinping.Dep
4、artmentofDermatology,HuashanHospital,FudanUniversity,Shanghai2D0D4D.C^inaCorrespondingalthOF"XuFeng,Email:xufeng@medmail.com.cn【Abstract】0bjectiveToinvestigatethedermoscopicfeaturesofandrogeneticalopecia(AGA)andtoassesstheirclinicalimplications.MethodsAhandhelddermoscopewasusedtoobservethebalding
5、scalpof200malepatientswithAGA(MAGA)。80femalepatientswithAGA(FAGA),aswellasnO1Tlalscalpof50humancontrolswithouthairloss.Clinicalinformationwasalsocollectedfromthesesubjects.ResultsOfthemaleandfemaleAGApatients.100.0%and88.8%showedhairdiameterdiversity(HDD)>20%inthebaldingareasrespectively.47.0%and
6、41.3%showedbrownperipilarsignrespectively.and23.5%and17.5%showedwhiteperipilarsignrespectively.35.0%and38.8%showedscalppigmentationrespectively.Yellowdotswereobservedin22.5%.31.3%and14.0%ofthemaleAGApatients。femaleAGApatientsandcontrolsrespectively,pinpointwhitedotsin24.O%,23.8%and18%respectively
7、,focalatrichiain28.5%,67.5%and2.0%respectively,andscalingin49.0%.56-3%and50.0%respectively.TheincidencerateofHDD>20%wassignificantlylower,butthatoffocalatfichiawassignificantlyhigherrinfemaleAGApatientsthaninmaleAGApat
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